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photograph of miSHERLOCK devices against a white background
A Self-Contained COVID-19 Test with 3-D Printed Parts
The makers of the CRISPR-based testing platform, called miSHERLOCK, say it could enable people at home or physicians in resource-limited environments to detect SARS-CoV-2—and eventually, other pathogens.
A Self-Contained COVID-19 Test with 3-D Printed Parts
A Self-Contained COVID-19 Test with 3-D Printed Parts

The makers of the CRISPR-based testing platform, called miSHERLOCK, say it could enable people at home or physicians in resource-limited environments to detect SARS-CoV-2—and eventually, other pathogens.

The makers of the CRISPR-based testing platform, called miSHERLOCK, say it could enable people at home or physicians in resource-limited environments to detect SARS-CoV-2—and eventually, other pathogens.

CRISPR

Hong Kong skyline with a pink sky in the background
Book excerpt from CRISPR People
Henry T. Greely | Aug 1, 2021 | 9 min read
In Chapter 6, author Henry T. Greely describes how news of the birth of gene-edited babies rocked a 2018 summit on human genome editing.
Opinion: How Biomedicine Could Transform Human Reproduction
Henry T. Greely | Aug 1, 2021 | 3 min read
CRISPR and other innovations are likely to open up a wealth of new options for how people have children.
Direct Capture of Guide RNAs Enables Scalable and Combinatorial Single-Cell CRISPR Screens
The Scientist | 1 min read
10x Genomics invites you to join them for an educational webinar.
photo of marshy wetland in california at sunset
Researchers Find DNA “Borgs” in Methane-Chomping Archaea
Annie Melchor | Jul 20, 2021 | 3 min read
Massive extrachromosomal elements named after the hive-minded cyborg villains in Star Trek may be the first of their kind.
cartoon showing a hand taking a tool to a double-helix of DNA to represent gene editing
WHO Releases New Recommendations on Human Genome Editing
Annie Melchor | Jul 12, 2021 | 3 min read
The guidance comes after two years of consulting with hundreds of stakeholders, including indigenous peoples, religious leaders, patient groups, and scientists.
Cellecta: Simplified Gene Functional Analysis
The Scientist | 1 min read
Discover high-throughput screening and profiing technologies to find and characterize novel therapeutic targets and drugs.
photograph of a woman wearing a face mask embedded with SARS-CoV-2 sensors
Researchers Create Pathogen-Sensing Face Mask
Annie Melchor | Jul 5, 2021 | 5 min read
The masks contain freeze-dried, cell-free biosensors, enabling them to detect pathogens including SARS-CoV-2.
Updated June 1
Head shot of Eric Lander, the president and founding director of the Broad Institute of MIT and Harvard
Science Advisor Nominee Faces Tough Questions from Senate Panel
Jef Akst | Apr 30, 2021 | 2 min read
Senators raise concerns about how Eric Lander of the Broad Institute has handled equality issues.
Synthego: Transforming the energy sector with CRISPR
The Scientist | 1 min read
New technology is required to increase bioenergy production. CRISPR may be the answer.
giraffe, genetics & genomics, CRISPR, gene editing, genome, physiology, hypertension, bone growth, techniques, mouse model
Genome Reveals Clues to Giraffes’ “Blatantly Strange” Body Shape
Amanda Heidt | Mar 19, 2021 | 5 min read
The physiological demands of that long neck get support from a gene involved in strengthening bones and blood vessels, researchers find after inserting the sequence in mice.
Opinion: Europe Is Sinking Biotech—Again
Robert Paarlberg | Feb 1, 2021 | 3 min read
Scientifically groundless regulations could undercut the potential of gene-edited crops, much as they have with GMOs.
Biden Names Geneticist Eric Lander as Top Science Adviser
Max Kozlov | Jan 18, 2021 | 3 min read
If confirmed, Lander will head the Office of Science and Technology Policy, a position that President Donald Trump left vacant for 18 months at the beginning of his term.
New Screening Approach Reveals Novel Regulators of Microcephaly
Catherine Offord | Jan 1, 2021 | 2 min read
Researchers combine organoids, CRISPR-Cas9, and cellular barcoding technologies to identify genes that influence brain size.
feluda cas9 fncas9 covid-19 sars-cov-2 diagnostics coronavirus pandemic india
Assay for Sickle Cell Anemia Is Repurposed to Diagnose COVID-19
G.B.S.N.P. Varma | Nov 18, 2020 | 5 min read
A CRISPR-based, paper-strip test developed by Indian researchers performs as well as real-time PCR in identifying the presence of SARS-CoV-2 and returns results within an hour.
CRISPR, Cas-9, Nobel, Chemistry
CRISPR’s Adaptation to Genome Editing Earns Chemistry Nobel
Amanda Heidt | Oct 7, 2020 | 4 min read
Emmanuelle Charpentier and Jennifer Doudna reprogrammed the bacterial immune response into one of the most popular tools for genetics and molecular biology.
aav adeno-associated virus vector gene therapy antibody hemophilia
Thwarting AAV-Neutralizing Antibodies Could Improve Gene Therapy
Emma Yasinski | Sep 25, 2020 | 5 min read
Adeno-associated viral vectors can deliver gene therapies, but AAV-neutralizing antibodies might prevent the medicines from working.
Panel Lays Out Guidelines for CRISPR-Edited Human Embryos
Lisa Winter | Sep 4, 2020 | 2 min read
The International Commission on the Clinical Use of Human Germline Genome Editing claims the technology is still too risky for therapeutic use.
Toward COVID-19 Testing Any Time, Anywhere
Abby Olena, PhD | Sep 2, 2020 | 7 min read
Researchers are adapting CRISPR, synthetic biology, and other creative approaches to detect SARS-CoV-2 nucleic acids outside of the lab or doctors’ offices, in the hopes of making diagnostics more affordable and accessible.
CRISPR, TALENs, ZFNs, gene editing, base editing, mitochondria, DNA, mtDNA
New Gene Editing Tool Corrects Mutations in Mitochondrial DNA
Amanda Heidt | Jul 9, 2020 | 3 min read
An enzyme pulled from toxic bacteria can enter the organelle and perform single-nucleotide DNA swaps.
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