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tag pharmacology culture

A mutated cell with a spiky membrane
Mutations in Autism-Linked Gene Cause Membrane Mischief
Holly Barker, PhD, Spectrum | Jan 26, 2023 | 4 min read
Inactivating TAOK1 prompts tentacle-like protrusions to form all over a neuron’s surface, revealing the gene’s role in molding the membrane.
a human neuron illuminated in bright green on a black background.
Mitochondrial Metabolism Dictates Neurons’ Growth Rate
Katherine Irving | Jan 30, 2023 | 4 min read
Altering the rate of respiration in mitochondria changes how fast neurons grow, making mouse neurons grow more like human ones and vice versa, a study finds.
2022 Top 10 Innovations 
2022 Top 10 Innovations
The Scientist | Dec 12, 2022 | 10+ min read
This year’s crop of winning products features many with a clinical focus and others that represent significant advances in sequencing, single-cell analysis, and more.
Using Temperature-Sensitive Channels to Study Neural Circuitry
Devika G. Bansal | Nov 1, 2018 | 8 min read
Meet the researchers building a thermogenetic toolbox.
A Selection of CRISPR Proof-of-Principle Studies
Kelly Rae Chi | Mar 1, 2017 | 7 min read
Advice on how to deploy the latest techniques in your own lab
The Proteasome: A Powerful Target for Manipulating Protein Levels
John Hines and Craig M. Crews | May 1, 2017 | 10+ min read
The proteasome’s ability to target and degrade specific proteins is proving useful to researchers studying protein function or developing treatments for diseases.
Macrophages Play a Double Role in Cancer
Amanda B. Keener | Apr 1, 2018 | 10+ min read
Macrophages play numerous roles within tumors, leaving cancer researchers with a choice: eliminate the cells or recruit them.
Fascinated by Folding
Anna Azvolinsky | Aug 3, 2017 | 10 min read
Lila Gierasch uses biochemical tools to understand how linear chains of amino acids turn into complex three-dimensional structures.
Top 10 Innovations 2015
The Scientist | Dec 1, 2015 | 10+ min read
The newest life-science products making waves in labs and clinics
Guts and Glory
Anna Azvolinsky | Apr 1, 2016 | 9 min read
An open mind and collaborative spirit have taken Hans Clevers on a journey from medicine to developmental biology, gastroenterology, cancer, and stem cells.

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