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tag pharmacology developmental biology

Guts and Glory
Anna Azvolinsky | Apr 1, 2016 | 9 min read
An open mind and collaborative spirit have taken Hans Clevers on a journey from medicine to developmental biology, gastroenterology, cancer, and stem cells.
Surpassing the Law of Averages
Jeffrey M. Perkel | Sep 1, 2009 | 7 min read
By Jeffrey M. Perkel Surpassing the Law of Averages How to expose the behaviors of genes, RNA, proteins, and metabolites in single cells. By necessity or convenience, almost everything we know about biochemistry and molecular biology derives from bulk behavior: From gene regulation to Michaelis-Menten kinetics, we understand biology in terms of what the “average” cell in a population does. But, as Jonathan Weissman of the University of Califo
Centrifuge Improvements Put New Spin On A Laboratory Workhorse
Howard Goldner | Mar 5, 1995 | 7 min read
A true laboratory workhorse, the centrifuge has been an essential part of most biological labs for many years. Using centrifugal force obtained by spinning experimental samples at high revolutions per minute (rpm), the device functions as a preparative method to separate various sample components, within minutes, for further treatment. Ultracentrifugation is an even more powerful technique that is used in analytical studies involving the characterization of and interactions between biological m
The AIDS Research Evaluators
Lynn Gambale | Jul 9, 1995 | 6 min read
Chairman: Arnold Levine, chairman, department of molecular biology, Princeton University Barry Bloom, Weinstock Professor and Howard Hughes Medical Institute (HHMI) investigator, department of microbiology and immunology, Albert Einstein College of Medicine, New York Rebecca Buckley, professor of pediatrics and immunology, Duke University Medical Center Charles Carpenter, chairman, Office of AIDS Research Advisory Committee; professor of medicine,Brown University School of Medicine Don
How Orphan Drugs Became a Highly Profitable Industry
Diana Kwon | May 1, 2018 | 10+ min read
Government incentives, advances in technology, and an army of patient advocates have spun a successful market—but abuses of the system and exorbitant prices could cause a backlash.
A Selection of CRISPR Proof-of-Principle Studies
Kelly Rae Chi | Mar 1, 2017 | 7 min read
Advice on how to deploy the latest techniques in your own lab
How Cells Find Their Way
Laura Defrancesco | Sep 2, 2001 | 5 min read
Organisms need to sense their environment. By sensing, they can develop, heal wounds, protect against invaders, and create blood vessels. Chemotaxis, or directional sensing, allows cells to detect chemicals with exquisite sensitivity. Some chemotactic cells can sense chemical gradients that differ by only a few percent from a cell's front to its back. Although discovery of the molecule types involved in chemotaxis, as with other kinds of cell signaling events, has mounted, the details of how thi
Brains in Action
The Scientist | Feb 1, 2014 | 10+ min read
Neuroscientists are automating neural imaging and recording, allowing them to monitor increasingly large swaths of the brain in living, behaving animals.
 
Top 10 Innovations 2012
The Scientist | Dec 1, 2012 | 10+ min read
The Scientist’s 5th installment of its annual competition attracted submissions from across the life science spectrum. Here are the best and brightest products of the year.
-Secretase Makes a Splash
Nicole Johnston(njohnston@the-scientist.com) | Jul 3, 2005 | 6 min read
It started as a matter of guilt by association.

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