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image: Rethinking a Cancer Drug Target

Rethinking a Cancer Drug Target

By | March 26, 2017

The results of a CRISPR-Cas9 study suggest that MELK—a protein thought to play a critical role in cancer—is not necessary for cancer cell survival.

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image: CRISPR-Based Therapy Prevents Retinal Degeneration

CRISPR-Based Therapy Prevents Retinal Degeneration

By | March 14, 2017

An experimental treatment sacrifices rod cell function to save cone cells in mice, preventing retinal degeneration, researchers report. 

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image: A Selection of CRISPR Proof-of-Principle Studies

A Selection of CRISPR Proof-of-Principle Studies

By | March 1, 2017

Advice on how to deploy the latest techniques in your own lab

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image: Smallest Cas9 Ortholog Reported

Smallest Cas9 Ortholog Reported

By | February 23, 2017

Researchers demonstrate the delivery of AAV-packaged CRISPR-CjCas9 into the muscles and eyes of mice.

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image: Broad Wins CRISPR Patent Interference Case

Broad Wins CRISPR Patent Interference Case

By | February 15, 2017

The USPTO’s Patent Trial and Appeal Board has ruled in favor of the Broad Institute of MIT and Harvard retaining intellectual property rights covered by its patents for CRISPR gene-editing technology.

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The Donald Danforth Plant Science Center researcher links complex traits to the genes that underlie them.

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image: ACMG Urges Caution When Editing Embryo Genomes

ACMG Urges Caution When Editing Embryo Genomes

By | January 30, 2017

The American College of Medical Genetics and Genomics calls on scientists and health care providers to engage in public discussion about the ethical issues involved in genome editing. 

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image: Improved Semisynthetic Organism Created

Improved Semisynthetic Organism Created

By | January 23, 2017

Researchers generate an organism that can replicate artificial base pairs indefinitely.

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image: Jeremy Day Probes Reward Signaling in the Brain

Jeremy Day Probes Reward Signaling in the Brain

By | January 1, 2017

The University of Alabama, Birmingham, researcher seeks the neural roots of animal behavior

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image: More Anti-CRISPR Proteins to Block Cas9

More Anti-CRISPR Proteins to Block Cas9

By | December 29, 2016

The latest CRISPR deactivators to be discovered turn off the Streptococcus pyogenes Cas9 widely used in genome editing.

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