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Scientists hope to save oranges from a bacterial disease that causes citrus greening, a disease that leads to bitter, discolored fruit.

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Scientists shut down cancer-causing fusion genes with CRISPR.

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image: RNAi’s Future in Drug-Target Screening

RNAi’s Future in Drug-Target Screening

By | April 17, 2017

A recent CRISPR study contradicted years of RNA interference research on a well-studied cancer drug target. But is it the last nail in the coffin for RNAi as a screening tool? 

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image: CRISPR-Based Nucleic Acid Test Debuts

CRISPR-Based Nucleic Acid Test Debuts

By | April 13, 2017

SHERLOCK combines CRISPR-Cas13a with isothermal RNA amplification to detect RNA and DNA with single-base specificity.

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image: CRISPR Corrects Duchenne-Causing Mutations

CRISPR Corrects Duchenne-Causing Mutations

By | April 12, 2017

Using CRISPR-Cpf1 gene editing, researchers have fixed mutations that cause a form of muscular dystrophy in cultured human cardiomyocytes and a mouse model.

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image: CRISPR Screen Detects Functional Gene Regulation

CRISPR Screen Detects Functional Gene Regulation

By | April 3, 2017

A CRISPR-Cas9–based method probes the regulatory roles of noncoding DNA sequences.

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image: Rethinking a Cancer Drug Target

Rethinking a Cancer Drug Target

By | March 26, 2017

The results of a CRISPR-Cas9 study suggest that MELK—a protein thought to play a critical role in cancer—is not necessary for cancer cell survival.

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image: CRISPR-Based Therapy Prevents Retinal Degeneration

CRISPR-Based Therapy Prevents Retinal Degeneration

By | March 14, 2017

An experimental treatment sacrifices rod cell function to save cone cells in mice, preventing retinal degeneration, researchers report. 

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image: A Selection of CRISPR Proof-of-Principle Studies

A Selection of CRISPR Proof-of-Principle Studies

By | March 1, 2017

Advice on how to deploy the latest techniques in your own lab

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image: Smallest Cas9 Ortholog Reported

Smallest Cas9 Ortholog Reported

By | February 23, 2017

Researchers demonstrate the delivery of AAV-packaged CRISPR-CjCas9 into the muscles and eyes of mice.

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