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image: Was a Drop in CRISPR Firms’ Stock Warranted?

Was a Drop in CRISPR Firms’ Stock Warranted?

By | June 7, 2017

A study of off-target effects that sparked fear among investors of genome-editing companies receives methodological criticisms.

5 Comments

image: Smallest Cas9 Ortholog Reported

Smallest Cas9 Ortholog Reported

By | February 23, 2017

Researchers demonstrate the delivery of AAV-packaged CRISPR-CjCas9 into the muscles and eyes of mice.

0 Comments

image: Jeremy Day Probes Reward Signaling in the Brain

Jeremy Day Probes Reward Signaling in the Brain

By | January 1, 2017

The University of Alabama, Birmingham, researcher seeks the neural roots of animal behavior

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image: More Anti-CRISPR Proteins to Block Cas9

More Anti-CRISPR Proteins to Block Cas9

By | December 29, 2016

The latest CRISPR deactivators to be discovered turn off the Streptococcus pyogenes Cas9 widely used in genome editing.

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image: New CRISPR-Cas Enzymes Discovered

New CRISPR-Cas Enzymes Discovered

By | December 22, 2016

A metagenomics analysis finds Cas9 in archaea for the first time, along with two previously unknown Cas nucleases from bacteria.

1 Comment

image: Keeping CRISPR in Check

Keeping CRISPR in Check

By | December 14, 2016

In bacteriophage genomes, researchers find three anti-CRISPR proteins that naturally inhibit CRISPR-Cas9 in one bacterial species and can do the same in human cells. 

1 Comment

image: CRISPR Oral Arguments Recap, Cont’d

CRISPR Oral Arguments Recap, Cont’d

By | December 8, 2016

This week’s CRISPR patent hearing took a deep dive into the science of moving the gene-editing technology from prokaryotes to eukaryotic systems.

2 Comments

image: Top 10 Innovations 2016

Top 10 Innovations 2016

By | December 1, 2016

This year’s list of winners celebrates both large leaps and small (but important) steps in life science technology.

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image: Targeting the Noncoding Genome with CRISPR

Targeting the Noncoding Genome with CRISPR

By | September 29, 2016

Two independent groups demonstrate the utility of CRISPR-based techniques to identify regulatory elements that govern disease-linked genes. 

1 Comment

image: Toggling CRISPR Activity with a Chemical Switch

Toggling CRISPR Activity with a Chemical Switch

By | September 12, 2016

Researchers design a Cas9 enzyme that cuts DNA only in the presence of particular drug.

0 Comments

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