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tag phosphorylation cell molecular biology

DNA molecule.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD | Mar 7, 2024 | 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 
Microfluidics: Biology’s Liquid Revolution
Laura Tran, PhD | Feb 26, 2024 | 8 min read
Microfluidic systems redefined biology by providing platforms that handle small fluid volumes, catalyzing advancements in cellular and molecular studies.
Microscopic image of a live amoeba.
Illuminating Specimens Through Live Cell Imaging
Charlene Lancaster, PhD | Mar 14, 2024 | 8 min read
Live cell imaging is a powerful microscopy technique employed by scientists to monitor molecular processes and cellular behavior in real time.
Molecular Biology
The Scientist Staff | Mar 3, 1991 | 2 min read
C. Ellis, M. Moran, F. McCormick, T. Pawson, "Phosphorylation of GAP and GAP-associated proteins by transforming and mitogenic tyrosine kinases," Nature, 343, 377-81, 25 January 1990. D.R. Kaplan, D.K. Morrison, G. Wong, F. McCormick, L.T. Williams, "PDGF b-receptor stimulates tyrosine phosphorylation of GAP and association of GAP with a signaling complex," Cell, 61, 125-33, 6 April 1990. Frank McCormick (Cetus Corp., Emeryville, Calif.): "GTPase-activating protein (GAP) is a protein that bin
Molecular Biology
The Scientist Staff | Sep 1, 1991 | 1 min read
S. Ghosh, D. Baltimore, "Activation in vitro of NF-kB by phosphorylation of its inhibitor IkB," Nature, 344:678-82, 1990. Sankar Ghosh (Whitehead Institute for Biomedical Research, Cambridge, Mass.): "This paper brings together two areas of rapidly moving research: the role of protein phosphorylation and control of transcriptional regulation. The inhibitor IkB not only keeps the transcription factor NF-kB in the cytoplasm--away from DNA--but also directly prevents it from binding to DNA. By sh
Green and red fluorescent proteins in a zebrafish outline the animal’s vasculature in red and lymphatic system in green in a fluorescent image. Where the two overlap along the bottom of the animal is yellow.
Serendipity, Happenstance, and Luck: The Making of a Molecular Tool
Shelby Bradford, PhD | Dec 4, 2023 | 10+ min read
The common fluorescent marker GFP traveled a long road to take its popular place in molecular biology today.
Molecular Biology
The Scientist Staff | Nov 8, 1992 | 2 min read
L.D. Kerr, J.-I. Inoue, N. Davis, E. Link, et al., "The Rel- associated pp40 protein prevents DNA binding of Rel and NF-kB: relationship with IkBb and regulation by phosphorylation," Genes & Development, 5:1464-76, 1991. Lawrence Kerr (The Salk Institute, La Jolla, Calif.): "The regulation of protooncogene Rel, a transcription factor belonging to the family of NF-kB transcription factors, is important for the well-being of the cell because its altered form, v-rel, causes lymphoid leukemias. Wh
Molecular Biology
The Scientist Staff | Feb 20, 1994 | 2 min read
S. Matsuda, H. Kosako, K. Takenaka, K. Moriyama, H. Sakai, T. Akiyama, Y. Gotoh, E. Nishida, "Xenopus MAP kinase activator: identification and function as a key intermediate in the phosphorylation cascade," The EMBO Journal, 11:973-82, 1992. Eisuke Nishida (Department of Genetics and Molecular Biology, Institute for Virus Research, Kyoto University, Japan): "MAP kinases have been described as serine/threonine kinases that are acti
A close up of several modular puzzle pieces.
Making Connections: Click Chemistry and Bioorthogonal Chemistry
Deanna MacNeil, PhD | Feb 13, 2024 | 5 min read
Simple, quick, and modular reactions allow researchers to create useful molecular structures from a wide range of substrates.
Collage of images including sperm, bacteria, coral, and an illustration of a researcher
Our Favorite Cell and Molecular Biology Stories of 2021
Jef Akst | Dec 2, 2021 | 3 min read
Beyond The Scientist’s coverage of COVID-19’s molecular underpinnings were many other stories highlighting the advances made in scientists’ understanding of the biology of cells.

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