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tag biophysics developmental biology

Collage of images including sperm, bacteria, coral, and an illustration of a researcher
Our Favorite Cell and Molecular Biology Stories of 2021
Jef Akst | Dec 2, 2021 | 3 min read
Beyond The Scientist’s coverage of COVID-19’s molecular underpinnings were many other stories highlighting the advances made in scientists’ understanding of the biology of cells.
Centrifuge Improvements Put New Spin On A Laboratory Workhorse
Howard Goldner | Mar 5, 1995 | 7 min read
A true laboratory workhorse, the centrifuge has been an essential part of most biological labs for many years. Using centrifugal force obtained by spinning experimental samples at high revolutions per minute (rpm), the device functions as a preparative method to separate various sample components, within minutes, for further treatment. Ultracentrifugation is an even more powerful technique that is used in analytical studies involving the characterization of and interactions between biological m
The AIDS Research Evaluators
Lynn Gambale | Jul 9, 1995 | 6 min read
Chairman: Arnold Levine, chairman, department of molecular biology, Princeton University Barry Bloom, Weinstock Professor and Howard Hughes Medical Institute (HHMI) investigator, department of microbiology and immunology, Albert Einstein College of Medicine, New York Rebecca Buckley, professor of pediatrics and immunology, Duke University Medical Center Charles Carpenter, chairman, Office of AIDS Research Advisory Committee; professor of medicine,Brown University School of Medicine Don
How to Create a Successful Fish Tale?
A. J. S. Rayl | Aug 19, 2001 | 10+ min read
More than 80 percent of the planet's living organisms exist only in aquatic ecosystems. Some may harbor secrets to human origins, and clues, treatments--perhaps even cures--for human disease. Some are critical bioindicators that portend the health of the biosphere. Yet, overall, scientists know little about the biochemical processes of these life forms. The vast, rich knowledge within the oceans and freshwater systems on Earth remains virtually untapped, because in the world of biological resear
Longevity
Jill Adams(juadams@the-scientist.com) | May 8, 2005 | 7 min read
During autophagy-literally "self-eating"-cells deliver cytoplasmic constituents, including whole organelles, to the lysosome for degradation.
The Shape of Heredity
Susan M. Gasser | Jul 1, 2009 | 10+ min read
By Susan M. Gasser The Shape of Heredity Tracking the dance of DNA and structural proteins within the nucleus shows that placement makes the difference between gene activity and silence. What's true of the best architecture is also true of cellular structures: form follows function. We biologists often take this mantra to an extreme, searching for the function of a molecule or gene without much consideration of its structure, its phys
A Peek at the Pore
Bennett Daviss(bdaviss@the-scientist.com) | Apr 24, 2005 | 6 min read
As the gateway to the nucleus, the nuclear pore complex manages hundreds of intricate cargo-handling operations every second.
Building a Better Biosensor
Mike May | May 23, 2004 | 8 min read
A GRADIENT OF PORE SIZES:Courtesy of Michael J. Sailorimparts a rainbow of colors to a porous silicon chip, one of a variety of new biosensor technologies in development around the world. The different colors correspond to different sized pores, ranging from a few nanometers to hundreds of nanometers in diameter. These pores help the device discriminate and detect proteins and other molecules based on their size.One morning in March 1995, the deadly nerve gas sarin wafted through the Tokyo subwa
Pursuing Proteomes
Deborah Wilkinson | Jun 11, 2000 | 9 min read
Bio-Rad's PROTEAN® IEF System provides 2-D electrophoretic separation as part of the ProteomeWorks System Australian postdoctoral fellow Marc Wilkins coined the term "proteome" in the mid-'90s, referring to the total set of proteins expressed in a given cell at a given time. The term took hold, and a new scientific discipline was born. In proteomic studies, all the proteins from a given cell, organelle, or tissue are analyzed simultaneously with respect to properties such as expression leve
One Step Beyond: Going Beyond Genomics With Proteomics And Two-Dimensional Gel Technology
Laura Defrancesco | Jan 3, 1999 | 10+ min read
Proteomes and 2D Gel Apparatus Providers Big science has moved on to proteins. With the new brand of science termed proteomics--named by the Australians Marc Wilkins and Keith Williams to mean the "set of PROTEins encoded by the genOME"--the push is on around the globe to produce a complete description of a cell/tissue/organism in terms of the proteins produced. The challenge is all the greater because the expressed protein pattern changes with time and environment--responding to developmenta

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