The Scientist

» epigenetics, immunology and disease/medicine

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image: Methylation Maestro

Methylation Maestro

By | January 1, 2017

After initially discovering that DNA methylation represses transcription, Howard Cedar continues to explore how the epigenetic mark regulates gene expression.

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image: Pharma Redo

Pharma Redo

By | January 1, 2017

Steve Braun of Cures Within Reach, a nonprofit focused on breathing new life into old medicines, describes the potential benefits of drug repurposing.

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image: Transgenerational Epigenetics Prepares Plants for Drought

Transgenerational Epigenetics Prepares Plants for Drought

By | January 1, 2017

Plants grown in dry soil produce offspring that are hardier in drought conditions, and DNA methylation appears responsible. 

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Oncologists have raised concerns about a mouse study that suggests the vaccine for human papillomavirus could cause brain damage.

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image: Mouse Immunology Paper Retracted

Mouse Immunology Paper Retracted

By | December 16, 2016

A finding of misconduct spurs the retraction of a Science paper claiming to have identified a protein in mice that boosted immunity to both viruses and cancer.

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image: Induced Pluripotent Stem Cells Show Signs of Donor Age

Induced Pluripotent Stem Cells Show Signs of Donor Age

By | December 12, 2016

iPSCs created through the reprogramming of human somatic cells retain genomic marks of the donor’s age.

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image: Naive T Cells Find Homes in Lymphoid Tissue

Naive T Cells Find Homes in Lymphoid Tissue

By | December 2, 2016

The human lymph nodes and spleen maintain unique, compartmentalized sets of naive T cells well into old age.

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image: Oligonucleotide Therapeutics Near Approval

Oligonucleotide Therapeutics Near Approval

By | December 1, 2016

Successful late-stage clinical trials could mark the maturation of a new drug development platform, but the path to commercialization is not without hurdles.

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image: Low Social Status May Weaken Immune System in Monkeys

Low Social Status May Weaken Immune System in Monkeys

By | November 29, 2016

Life at the bottom of the pecking order ramps up inflammation, according to new research, an effect that appears to be reversible.

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image: How Diet Influences Host-Microbiome Communication in Mice

How Diet Influences Host-Microbiome Communication in Mice

By | November 23, 2016

Researchers are beginning to decipher the metabolic language of the microbiome, and determine how gut microbes communicate with host tissue.

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