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image: Epigenetic Changes Can Cause Cancer

Epigenetic Changes Can Cause Cancer

By | July 25, 2014

A transgene designed to attract methylation to the promoter of a tumor-suppressor gene leads to tumorigenesis in a mouse model. 

4 Comments

image: Week in Review: July 7–11

Week in Review: July 7–11

By | July 11, 2014

Assessing mtDNA mutations among healthy people; heritability of intelligence; epigenetic inheritance of maternal malnutrition markers; consumers buy into DNA ancestry

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image: Gestational Malnutrition Affects Offspring’s Sperm

Gestational Malnutrition Affects Offspring’s Sperm

By | July 10, 2014

Mice undernourished during pregnancy can transmit the effects of such nutritional stress to their sons’ germ cells, epigenetically.  

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image: Epigenetic Effects of Mom’s Diet

Epigenetic Effects of Mom’s Diet

By | April 29, 2014

Molecular markers of a mother’s nutrition around the time of conception can be found in her child’s DNA.

4 Comments

image: Week in Review: April 14–18

Week in Review: April 14–18

By | April 18, 2014

Genome-wide effects of trisomy 21; RNA-based signs of transgenerational stress; depression and resilience; a call to overhaul US biomedical research system

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image: Traces of Trauma in Sperm RNA

Traces of Trauma in Sperm RNA

By | April 13, 2014

A mouse study shows that molecular remnants of early-life stress can be passed on to future generations.

3 Comments

image: Epigenetic Cancer Therapy Clears Phase I

Epigenetic Cancer Therapy Clears Phase I

By | April 7, 2014

Investigational drug that inhibits proteins involved with epigenetic regulation shows activity against certain blood cancers in an early-stage clinical trial.

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image: Unmasking Secret Identities

Unmasking Secret Identities

By | February 1, 2014

A tour of techniques for measuring DNA hydroxymethylation

2 Comments

image: Daytime Sleep Alters Human Transcriptome

Daytime Sleep Alters Human Transcriptome

By | January 20, 2014

A mistimed sleep cycle drastically reduces the number of genes that are expressed in a 24-hour rhythm.

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image: Inherited Fears

Inherited Fears

By | December 2, 2013

Mice appear to pass certain fears onto their offspring, according to a new study.

1 Comment

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