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image: Adipocyte-Derived DNA Triggers Inflammation

Adipocyte-Derived DNA Triggers Inflammation

By | March 25, 2016

DNA released from dying fat cells stimulates inflammation within murine fat tissue. 

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image: Contributors

Contributors

By | November 1, 2015

Meet some of the people featured in the November 2015 issue of The Scientist.

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image: The Skinny on Fat Cells

The Skinny on Fat Cells

By | November 1, 2015

Bruce Spiegelman has spent his career at the forefront of adipocyte differentiation and metabolism.

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image: Breaking the Cancer-Obesity Link

Breaking the Cancer-Obesity Link

By , and | November 1, 2015

Obese people are at higher risk for developing cancer, have worse prognoses once diagnosed, and are often resistant to chemotherapy regimens. The question is, Why?

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image: A Complex Disorder

A Complex Disorder

By , and | November 1, 2015

Factors that likely contribute to obesity include disruptions to intercellular signaling, increased inflammation, and changes to the gut microbiome.  

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image: Warming Up to Brown Fat

Warming Up to Brown Fat

By | October 8, 2015

Scientists know how to turn on these fat-combusting cells. Can these energy burners be used to combat obesity?

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image: Neuronal Connection Between Fat and the Brain Visualized

Neuronal Connection Between Fat and the Brain Visualized

By | September 24, 2015

Researchers pinpoint the neurons within white fat tissue that mediate brain-bound leptin signaling and eventual fat breakdown.

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image: Burn Victims Produce Brown Fat

Burn Victims Produce Brown Fat

By | August 7, 2015

Following extreme trauma, patients’ adipose samples have revealed—for the first time in humans—that white fat can be converted into energy-burning brown fat.

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image: Bone Marrow Makes New Fat Cells

Bone Marrow Makes New Fat Cells

By | July 16, 2015

The origins of adipocytes have been hotly debated, but a human study supports the idea that the bone marrow takes part. 

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image: Brain’s Role in Browning White Fat

Brain’s Role in Browning White Fat

By | January 15, 2015

Insulin and leptin act on specialized neurons in the mouse hypothalamus to promote conversion of white to beige fat.

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