chromatin

Scientists established an epigenetic mouse model for glioma, providing insight into how epigenetics can initiate cancer.

Detailed analyses of cohesin’s movements indicate how this protein complex hauls chromatin fibers to package DNA into loops.

The hinge region of cohesin pulls DNA to two head regions, like a person’s hand-to-hand motion of pulling on a rope.

Genes lacking a particular structure known as CpG islands tend to go haywire in older cells, a study finds, potentially contributing to key facets of aging. But it’s not yet clear if the relationship is causal.

A report of preserved fragments of nuclei and chromatin in a fossilized femur of a 125-million-year-old Caudipteryx dinosaur elicits skepticism.

The dynamic behavior of a transcriptional activator can be used to specify the activity level of its target gene, a study suggests.

The transcription of DNA drives the remarkably tidy organization of chromosomes in the dinoflagellate Symbiodinium microadriaticum.

In mice, epigenetic marks made on histones during infancy influence depression-like behavior during adulthood. A drug that reverses the genomic tags appears to undo the damage.

The University of Oregon scientist studied the structure and function of chromatin, with the intent of designing new therapeutic tools.

PCR moves into the laundry room, while insect colonies take up residence in the shower.

The DNA-protein complex has branches that fold back on themselves.

The Dana-Farber Cancer Institute researcher is developing cancer therapeutics based on how the physical structure of DNA contributes to the disease.

Telomeres in cancer cells exposed to oxidative stress got shorter and stickier.

Researchers describe their tools for probing how the physical shape of the genome affects genes’ function.

Researchers watch the protein condensin in action.