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image: Image of the Day: Placental Array

Image of the Day: Placental Array

By | April 26, 2017

Placentas from mice with genetically distinct immune systems, stained to highlight differences in three proteins, representing the nucleus (blue), blood vessels (red), and trophoblasts (green)

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image: An Epigenetic Aging Clock for Mice

An Epigenetic Aging Clock for Mice

By | April 21, 2017

Scientists predict rodents’ ages by assessing DNA methylation markers in various tissues.

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A mouse study reveals a causal link between changes in intestinal microbiota and increasing inflammation as the rodents age.

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Mice exposed to low doses of penicillin in utero or as young pups exhibited long-term behavioral differences not seen in their non-exposed counterparts, according to a study.

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image: Viral Trigger for Celiac Disease?

Viral Trigger for Celiac Disease?

By | April 6, 2017

A common, seemingly benign human virus can trigger an immune response that leads to celiac disease in a mouse model, researchers show. 

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Recolonizing middle-aged animals with bacteria from younger ones kept killifish alive longer than usual, researchers report.

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image: Gel Scaffolds for Delivery of Immunotherapies

Gel Scaffolds for Delivery of Immunotherapies

By | April 1, 2017

Using biocompatible polymers to carry cancer immune therapies directly to the tumor

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image: Making CAR T-Cell Therapy Safer

Making CAR T-Cell Therapy Safer

By | April 1, 2017

Following a spate of patient deaths in clinical trials testing modified T cells for the treatment of cancer, researchers work to reduce the treatment’s toxicity without sacrificing efficacy.

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image: Neoantigens Enable Personalized Cancer Immunotherapy

Neoantigens Enable Personalized Cancer Immunotherapy

By | April 1, 2017

Tumors’ mutations can encode the seeds of their own destruction, in the form of immunogenic peptides recognized by T cells.

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image: Infographic: Antibody Cancer Therapy

Infographic: Antibody Cancer Therapy

By | April 1, 2017

An experimental technique removes T cells that aid in vitro tumor growth.

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