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Discrepancies in the populations’ immune systems suggest murine models of immunological disorders possess more limitations than scientists had appreciated.

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image: Polio Vaccine Pioneer Dies

Polio Vaccine Pioneer Dies

By | May 2, 2017

Julius Youngner collaborated with Jonas Salk on the polio vaccine, and later identified interferon gamma and contributed to an equine influenza vaccine.

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Time-lapse imaging shows the immune cells transferring chemical signals during pigment pattern formation in developing zebrafish.

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image: Infographic: How the Zebrafish Got Its Stripes

Infographic: How the Zebrafish Got Its Stripes

By | May 1, 2017

Immune cells called macrophages shuttle cellular messages in the skin.

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image: Image of the Day: Placental Array

Image of the Day: Placental Array

By | April 26, 2017

Placentas from mice with genetically distinct immune systems, stained to highlight differences in three proteins, representing the nucleus (blue), blood vessels (red), and trophoblasts (green)

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image: An Epigenetic Aging Clock for Mice

An Epigenetic Aging Clock for Mice

By | April 21, 2017

Scientists predict rodents’ ages by assessing DNA methylation markers in various tissues.

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image: Viral Trigger for Celiac Disease?

Viral Trigger for Celiac Disease?

By | April 6, 2017

A common, seemingly benign human virus can trigger an immune response that leads to celiac disease in a mouse model, researchers show. 

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image: Gel Scaffolds for Delivery of Immunotherapies

Gel Scaffolds for Delivery of Immunotherapies

By | April 1, 2017

Using biocompatible polymers to carry cancer immune therapies directly to the tumor

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image: Making CAR T-Cell Therapy Safer

Making CAR T-Cell Therapy Safer

By | April 1, 2017

Following a spate of patient deaths in clinical trials testing modified T cells for the treatment of cancer, researchers work to reduce the treatment’s toxicity without sacrificing efficacy.

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image: Neoantigens Enable Personalized Cancer Immunotherapy

Neoantigens Enable Personalized Cancer Immunotherapy

By | April 1, 2017

Tumors’ mutations can encode the seeds of their own destruction, in the form of immunogenic peptides recognized by T cells.

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