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tag mice disease medicine evolution genetics genomics
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD
| Mar 7, 2024
| 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening.
CRISPR Gene Drives and the Future of Evolution
Hannah Thomasy, PhD
| Mar 15, 2024
| 10+ min read
Genetic engineering pioneer Kevin Esvelt’s work highlights biotechnology’s immense potential for good—but also for catastrophe.
Identical Twins Carry Distinctive Epigenetic Marks: Study
Chloe Tenn
| Sep 30, 2021
| 2 min read
Researchers found more than 800 sites in the genome where the twins bore the same chemical tags.
Stem Cell Editing Repairs Severe Immunodeficiency
Kamal Nahas, PhD
| Mar 20, 2024
| 5 min read
Scientists hoping to treat immunodeficiencies using gene therapy have found a way to edit stem cells in mice without disrupting gene regulation.
Tasmanian Devils Face Threats from Rapidly Evolving Facial Cancers
Natalia Mesa, PhD
| Jun 30, 2023
| 3 min read
A genetic study tracked the evolution of two transmissible cancers currently ravaging populations of Tasmanian devils.
Ancient Viral DNA Helps Mouse Brains Fight Infection
Natalia Mesa, PhD
| Oct 24, 2022
| 3 min read
Mammals that give birth to live young may have evolved to make use of the remnants of viruses in their genomes to ward off pathogens, a study suggests.
Mice Pass Epigenetic Tweaks to Pups
Katherine Irving
| Feb 17, 2023
| 5 min read
An engineered methylation pattern persisted for four generations of mice, demonstrating transgenerational epigenetic inheritance can occur in mammals.
Humans Rely on Gut Bacteria for an Enzyme that Prevents Jaundice
Kamal Nahas, PhD
| Feb 16, 2024
| 5 min read
An absence of bilirubin-producing gut microbes may predispose individuals to some diseases, including inflammatory bowel disease.
Spiny Mice Appear to Regenerate Damaged Kidneys
Dan Robitzski
| Nov 3, 2021
| 5 min read
The mice, already known to regenerate skin, seem to avoid the tissue scarring that leads to organ failure in other animals.
Ancient Viral DNA Plays a Role in Human Disease and Development
Aidan Burn,
The Conversation
| Oct 19, 2022
| 4 min read
Viral remnants make up 8 percent of the human genome, and a new study finds that these sequences are still active in healthy people.
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