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tag mice disease medicine
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD
| Mar 7, 2024
| 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening.
Gut Bacteria Help T Cells Heal Muscle: Study
Natalia Mesa, PhD
| Mar 14, 2023
| 4 min read
Regulatory T cells in the colon travel to muscles to promote wound healing in mice, raising questions about how antibiotics may impact injury recovery.
How Pancreas Injuries Can Cause Cancer in Mice
Dan Robitzski
| Nov 9, 2021
| 4 min read
A key mutation turns healing cells into cancer promoters.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD
| Mar 15, 2024
| 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Immunotherapy Treats Fibrosis in Mice
Alejandra Manjarrez, PhD
| Sep 15, 2022
| 4 min read
Researchers report that vaccination against proteins found on profibrotic cells reduced liver and lung fibrosis in laboratory rodents.
Pancreatic Organoids Take the Stage
Laura Tran, PhD
| Dec 1, 2023
| 2 min read
Meritxell Huch tackled her pipedream of growing three-dimensional pancreatic tissue in a dish.
Antisense Oligonucleotides Cross Rodents’ Blood-Brain Barrier
Abby Olena, PhD
| Aug 18, 2021
| 3 min read
RNA-DNA complexes that were modified with cholesterol made it into the brains of rats and mice, where they knocked down target genes.
Defying Dogma: Decentralized Translation in Neurons
Danielle Gerhard, PhD
| Sep 8, 2023
| 10+ min read
To understand how memories are formed and maintained, neuroscientists travel far beyond the cell body in search of answers.
Bespoke Stem Cells for Brain Disease
Nsikan Akpan
| Jan 14, 2013
| 3 min read
Scientists use virus-free gene therapy on patient-derived stem cells to repair spinal muscular atrophy in mice.
Short-lived Molecules Support Long-term Memory
Alejandra Manjarrez, PhD
| Jun 6, 2023
| 3 min read
A gene essential for information storage in the brain engages an autoregulatory feedback loop to consolidate memory.
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