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image: Image of the Day: Placental Array

Image of the Day: Placental Array

By | April 26, 2017

Placentas from mice with genetically distinct immune systems, stained to highlight differences in three proteins, representing the nucleus (blue), blood vessels (red), and trophoblasts (green)

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The state’s board of education approves new standards that ease up on having students dig into scientific issues relevant to “intelligent design” arguments.

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image: An Epigenetic Aging Clock for Mice

An Epigenetic Aging Clock for Mice

By | April 21, 2017

Scientists predict rodents’ ages by assessing DNA methylation markers in various tissues.

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image: New Giant Virus Group Reported

New Giant Virus Group Reported

By | April 6, 2017

A genomic analysis of “Klosneuviruses” suggests that they evolved from small viruses that accumulated genetic material over time, but not all virologists are convinced. 

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image: Contributors

Contributors

By | April 1, 2017

Meet some of the people featured in the April 2017 issue of The Scientist.

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image: Hitting It Out of the Park

Hitting It Out of the Park

By | April 1, 2017

Cancer can be as evasive and slippery as a spitball, but new immunotherapies are starting to connect.

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image: Location, Location, Location

Location, Location, Location

By | April 1, 2017

Since first proposing that a cell’s function and biology depend on its surroundings, Mina Bissell continues to probe the role of the extracellular matrix.

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image: Making CAR T-Cell Therapy Safer

Making CAR T-Cell Therapy Safer

By | April 1, 2017

Following a spate of patient deaths in clinical trials testing modified T cells for the treatment of cancer, researchers work to reduce the treatment’s toxicity without sacrificing efficacy.

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Measuring PD-L1 levels was a great start. Now we need to quantify more protein biomarkers, assess the tumor mutational landscape, and examine immune cell signatures, too.

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image: Circadian Rhythms Influence Treatment Effects

Circadian Rhythms Influence Treatment Effects

By | April 1, 2017

Across many diseases, taking medication at specific times of day may make the therapy more effective.

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