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tag mice genetics genomics culture
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD
| Mar 7, 2024
| 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening.
All Roads Lead to Genome Editing
Danielle Gerhard, PhD
| Feb 9, 2024
| 6 min read
Shondra Pruett-Miller has taken many paths in her career with her love of genome editing always as a guiding light.
Delivering Prime Editors With Virus-like Particles
Deanna MacNeil, PhD
| Mar 11, 2024
| 3 min read
An iterative engineering approach to improve prime editor delivery helped scientists correct genetic vision defects in mice.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD
| Mar 15, 2024
| 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
CRISPR Gene Drives and the Future of Evolution
Hannah Thomasy, PhD
| Mar 15, 2024
| 10+ min read
Genetic engineering pioneer Kevin Esvelt’s work highlights biotechnology’s immense potential for good—but also for catastrophe.
The Cre-
loxP
System: A Powerful Tool in the Genetic Toolbox
Laura Tran, PhD
| Dec 4, 2023
| 9 min read
Standing at the cornerstone of genetic research, Cre-
loxP
recombination serves as molecular scissors for precisely manipulating the genome.
One Protein to Rule Them All
Shelby Bradford, PhD
| Feb 28, 2024
| 10+ min read
p53 is possibly the most important protein for maintaining cellular function. Losing it is synonymous with cancer.
Yeast Made to Harvest Light Hint at Evolution’s Past
Kamal Nahas, PhD
| Feb 21, 2024
| 6 min read
Scientists transferred light-harvesting proteins into yeast for the first time, shining a light on the past lives of eukaryotic cells.
Mice Pass Epigenetic Tweaks to Pups
Katherine Irving
| Feb 17, 2023
| 5 min read
An engineered methylation pattern persisted for four generations of mice, demonstrating transgenerational epigenetic inheritance can occur in mammals.
Early-Life Stress Exerts Long-Lasting Effects Via Epigenome
Asher Jones
| Mar 18, 2021
| 5 min read
In mice, epigenetic marks made on histones during infancy influence depression-like behavior during adulthood. A drug that reverses the genomic tags appears to undo the damage.
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