The Scientist

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Harvesting lab-raised zebrafish based on their size led to differences in the activity of more than 4,000 genes, as well as changes in allele frequencies of those genes, in the fish that remained.

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image: Quick and Cheap Zika Detection

Quick and Cheap Zika Detection

By | May 3, 2017

A heat block, a truck battery, and a novel RNA amplification assay make for in-the-field surveillance of the virus.

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From fish harvests to cottonwood forests, organisms display evidence that species change can occur on timescales that can influence ecological processes.

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Studies of infected rhesus monkeys reveal the virus’s long-term hiding places in the body.

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image: Another New Timeline for <em>Homo naledi</em>

Another New Timeline for Homo naledi

By | April 27, 2017

The ancient human may have lived around 200,000 to 300,000 years ago—much more recently than previously estimated.

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image: Contributors

Contributors

By | April 1, 2017

Meet some of the people featured in the April 2017 issue of The Scientist.

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image: Hitting It Out of the Park

Hitting It Out of the Park

By | April 1, 2017

Cancer can be as evasive and slippery as a spitball, but new immunotherapies are starting to connect.

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image: Location, Location, Location

Location, Location, Location

By | April 1, 2017

Since first proposing that a cell’s function and biology depend on its surroundings, Mina Bissell continues to probe the role of the extracellular matrix.

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image: Making CAR T-Cell Therapy Safer

Making CAR T-Cell Therapy Safer

By | April 1, 2017

Following a spate of patient deaths in clinical trials testing modified T cells for the treatment of cancer, researchers work to reduce the treatment’s toxicity without sacrificing efficacy.

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Measuring PD-L1 levels was a great start. Now we need to quantify more protein biomarkers, assess the tumor mutational landscape, and examine immune cell signatures, too.

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