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tag genetically modified microbiology

bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Haydeh Payami is wearing a purple dress and an orange and pink scarf and standing in front of a whiteboard.
A Microbial Link to Parkinson’s Disease
Mariella Bodemeier Loayza Careaga, PhD | Dec 4, 2023 | 6 min read
Haydeh Payami helped uncover the genetic basis of Parkinson’s disease. Now, she hopes to find new ways to treat the disease by studying the gut microbiome.
Bugs as Drugs to Boost Cancer Therapy
Danielle Gerhard, PhD | Jan 18, 2024 | 7 min read
Bioengineered bacteria sneak past solid tumor defenses to guide CAR T cells’ attacks.
bacteria inside a biofilm
How Bacterial Communities Divvy up Duties
Holly Barker, PhD | Jun 1, 2023 | 10+ min read
Biofilms are home to millions of microbes, but disrupting their interactions could produce more effective antibiotics.
T regulatory cell in red sandwiching an antigen presenting cell in blue
Gut Bacteria Help T Cells Heal Muscle: Study
Natalia Mesa, PhD | Mar 14, 2023 | 4 min read
Regulatory T cells in the colon travel to muscles to promote wound healing in mice, raising questions about how antibiotics may impact injury recovery.
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
The Role of Mom’s Microbes During Pregnancy
Carolyn A. Thomson and Kathy D. McCoy | Aug 1, 2021 | 10+ min read
Bacteria in the gut influence the production of antibodies and themselves secrete metabolites. In a pregnant woman, these compounds may influence immune development of her fetus.
Alfred Pühler
Cormac Sheridan | Jan 12, 2009 | 3 min read
Alfred Pühler Forty years (and counting) at the forefront of microbiology research have not dimmed Pühler's infectious enthusiasm or voracious work ethic. By Cormac Sheridan Alfred Pühler has been a powerhouse in German microbiological research—initially in the area of plant-microbe interactions and later in industrial microbiology—over the past four decades. But he actually started out in nuclear physics, obtain
Stem Cells: Safe Haven For TB
Nsikan Akpan | Feb 5, 2013 | 3 min read
Tuberculosis bacteria find shelter from drugs and the body’s defenses in bone marrow stem cells.
Research Notes
Eugene Russo | Jun 25, 2000 | 5 min read
Putting Polio to Good Use Add polio to a host of other viral and bacterial foes that, in modified forms, could prove therapeutically beneficial. Although Russian scientists attempted to use polio to treat cancer in the 1960s--unpublished experiments about which little is known--a recent brain cancer study in mice is the first modern-day attempt to harness the power of the virus (M. Gromeier et al., "Intergeneric poliovirus recombinants for the treatment of malignant glioma," Proceedings of the

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