vaccination

Synthetic variations of squalene, which is used to boost immune responses, could make vaccines more effective while reducing fisheries for struggling sharks.

Males recovered from mild COVID-19 have baseline immune states primed to mount stronger responses to future challenges.

Multiple candidates are in Phase 3 clinical trials for older adults and pregnant women, with some getting close to approval in the United States.

Researchers find that small sacks inside lymph nodes contain low proteolytic activity and act as safe havens for antigens.

A method for culturing the infectious stage of the Plasmodium lifecycle could increase malaria vaccine production efficiency by tenfold, study authors say.

He also worked on immunizations against polio, rubella, influenza, and more.

Researchers find signatures pre- and post-vaccination that correlate with a more robust immune response. 

Pregnancy-induced changes in the immune system are key to a successful birth. Understanding those changes could allow researchers to protect both mother and child.

Aberrant immune activation, the main cause of prematurity and stillbirths, could be preventable through interventions such as maternal vaccination. 

The international group coordinating emergency vaccines recommends administering one dose instead of two to combat the “dire shortage” of cholera vaccines worldwide.

Low booster rates and immune-evading SARS-CoV-2 variants could spell bad news, experts say. 

Researchers say they’re abandoning the project in its current form—one of several that aims to induce what’s known as mucosal immunity against SARS-CoV-2.

Recent studies have lent support for a variety of hypotheses explaining the debilitating symptoms affecting millions of people after SARS-CoV-2 infection.  

A vaccine strategy involving formulation changes, an initial escalating dose, and a longer wait for booster immunization results in more-effective antibody production against HIV in rhesus monkeys, a study finds.

Immune cells deliver packages of telomeres to T cells, helping them retain their virus-fighting function over time, research suggests.

Researchers report that vaccination against proteins found on profibrotic cells reduced liver and lung fibrosis in laboratory rodents.

The immunizations are designed to target the latest Omicron subvariants, and are only authorized for people who have already received their primary vaccinations.

Evidence thus far shows that pregnant people infected with SARS-CoV-2 are at higher risk for severe disease and death, as well as complications in their pregnancies.