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tag somatic mutations immunology evolution

A blood sample containing white and red blood cells.
Enhancing Cell Morphology-Based Analysis
The Scientist and Deepcell | Aug 3, 2023 | 3 min read
Learn how the latest AI-driven technology uses morphology to comprehensively analyze and sort cell populations.
Neoantigens Enable Personalized Cancer Immunotherapy
Stephen P. Schoenberger and Ezra Cohen | Apr 1, 2017 | 9 min read
Tumors’ mutations can encode the seeds of their own destruction, in the form of immunogenic peptides recognized by T cells.
On the left is a normally developing mouse embryo, on the right is a slightly larger mouse embryo that also contains horse cells that glow green.
Chimera research opens new doors to understanding and treating disease
Hannah Thomasy, PhD, Drug Discovery News | Aug 9, 2023 | 10 min read
Animals with human cells could provide donor organs or help us understand neuropsychiatric disorders.
Layered visual representation of multiomics
Integrate and Innovate with NGS and Multiomics
The Scientist and Illumina | May 4, 2023 | 6 min read
Researchers across disciplines combine layers of discovery obtained with accessible NGS-based multiomics approaches.
illustration of a mitochondrian inside a cell
Could Dad’s Mitochondrial DNA Benefit Hybrids?
Alejandra Manjarrez, PhD | Jan 20, 2022 | 7 min read
Studies have found that organisms can inherit mitochondria from male parents in rare instances, and both theoretical and experimental work hint that this biparental inheritance is more than just a fluke.
Defeating the Virus
Wayne C. Koff | May 1, 2015 | 10+ min read
Recent discoveries are spurring a renaissance in HIV vaccine research and development.
Top 10 Innovations 2021
2021 Top 10 Innovations
The Scientist | Dec 1, 2021 | 10+ min read
The COVID-19 pandemic is still with us. Biomedical innovation has rallied to address that pressing concern while continuing to tackle broader research challenges.
2018 Top 10 Innovations
The Scientist | Dec 1, 2018 | 10+ min read
Biology happens on many levels, from ecosystems to electron transport chains. These tools may help spur discoveries at all of life's scales.
Notable
Jeffrey Perkel | Feb 3, 2002 | 4 min read
T.J. Macke et al., "RNAMotif, an RNA secondary structure definition and search algorithm," Nucleic Acids Research, 29:4724-35, Nov. 15, 2001. F1000 Recommendation: Recommended "This paper describes a new computer program that allows searching of genomic sequence databases for complex RNA structural elements. RNAMotif represents a major technical advance over previously available tools in that it allows the user to specify multiple parameters, including non-canonical base-pairings and variabilit
Death in the Balance
Laura Defrancesco | Jun 24, 2001 | 5 min read
In 1997, to the surprise of many researchers, mitochondria reclaimed the limelight of apoptosis research when several groups observed that cytochrome c released from the mitochondria could induce apoptosis in cell-free systems.1,2 A hot research topic decades ago, mitochondria excitement cooled in the 1970s when researchers agreed on the mechanisms of oxidative phosphorylation (ox-phos). Now, mitochondria-mediated apoptosis is believed to be central to a number of major debilitating diseases, in

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