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tag phylogenetics genetics genomics

A Nile rat sitting atop fruits
Genome Spotlight: Nile Rat (Avicanthis niloticus)
Christie Wilcox, PhD | Nov 23, 2022 | 4 min read
A reference sequence for this emerging model organism will facilitate research on type 2 diabetes and the health effects of circadian rhythm disruption.
Histological slide showing cancerous prostate tissue
2D Genetic Map of Prostate Cells Charts Cancer Growth
Holly Barker, PhD | Aug 23, 2022 | 4 min read
An in situ map of copy number variations in prostate tissue reveals that purportedly cancerous genomic changes frequently occur in the healthy tissue surrounding tumors.
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
Notable
Jeffrey Perkel | May 12, 2002 | 3 min read
J.O. Korbel et al., "SHOT: A Web server for the construction of genome phylogenies," Trends in Genetics, 18[3]:158-62, March 1, 2002. "This paper reports the results of phylogenetic analysis using whole genome comparisons and introduces a new Web server (named "SHOT") for further analysis by gene-content and gene-order methods. Among the results, the gene-content method showed Homo sapiens to be more closely related to Drosophila melanogaster than Caenorhabditis elegans, and both methods showed
Genetic Parasites and a Whole Lot More
Barry Palevitz | Oct 15, 2000 | 10+ min read
Photo: Ori Fragman, Hebrew University Hordeum spontaneum, the plant studied for BARE-1 retroelements. With genome sequences arriving almost as regularly as the morning paper, the public's attention is focused on genes--new genes to protect crops against pests; rogue genes that make bacteria resistant to antibiotics; faulty genes that, if fixed, could cure diseases such as muscular dystrophy. What many people don't realize is that genes account for only part of an organism's DNA, and in many c
Bioinformatics, Genomics, and Proteomics
Christopher Smith | Nov 26, 2000 | 10+ min read
Data Mining Software for Genomics, Proteomics and Expression Data (Part 1) Data Mining Software for Genomics, Proteomics and Expression Data (Part 2) High-throughput (HT) sequencing, microarray screening and protein expression profiling technologies drive discovery efforts in today's genomics and proteomics laboratories. These tools allow researchers to generate massive amounts of data, at a rate orders of magnitude greater than scientists ever anticipated. Initiatives to sequence entire genom
Epigenetic Enigmas
Beth Marie Mole | Oct 16, 2012 | 3 min read
Overturning previous studies, a peculiar protozoan mysteriously uses a DNA-markup system to take out the genetic trash.   
Planning the Future of Plant Genomics
Eugene Russo | Jul 21, 2002 | 5 min read
Image: Courtesy of National Sciences Foundation Arabidopsis Plant genomics researchers stand at a crossroads. Behind them are the completed genome sequences of rice1 and the model mustard plant Arabidopsis thaliana.2 Now, armed with insights gained from both plant and animal sequencing projects, plant biologists must decide how to proceed with future sequencing, proteomics, and functional genomics endeavors--and how to allot precious basic research dollars while, at the same time, keeping
An illustration of green bacteria floating above neutral-colored intestinal villi
The Inside Guide: The Gut Microbiome’s Role in Host Evolution
Catherine Offord | Jul 1, 2021 | 10+ min read
Bacteria that live in the digestive tracts of animals may influence the adaptive trajectories of their hosts.
Bloody Isle
Newamul Khan | Apr 1, 2007 | 3 min read
Bloody Isle When genetics and history compete, who wins?By Newamul Khan ARTICLE EXTRASSPRING BOOKSStem Cells on ShelvesAn Awkward SymbiosisThe Death of Faith?High in the TreesThe Enchantment of EnhancementBooks about BodiesNew Lab ManualsIn Brief Saxons, Vikings, and Celts: The Genetic Roots of Britain and Ireland, By Bryan Sykes, 320

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