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By implanting patient- or rodent-derived mini-guts into mice, scientists can rapidly create more-accurate murine models of the disease

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A cell phone–based microscope can identify mutations in tumor tissue and image products of DNA sequencing reactions.

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Member, Department of Immunology, St. Jude Children’s Research Hospital. Age: 43

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image: Guts and Glory

Guts and Glory

By | April 1, 2016

An open mind and collaborative spirit have taken Hans Clevers on a journey from medicine to developmental biology, gastroenterology, cancer, and stem cells.

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image: Managing Methylation

Managing Methylation

By | January 1, 2016

A long noncoding RNA associated with DNA methylation has the power to regulate colon cancer growth in vitro.

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image: Organoid Biobank

Organoid Biobank

By | May 11, 2015

From the tissue of numerous colon cancer patients, researchers build 3-D cultures of tumors.

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image: High-Tech Yogurt Could Detect Disease

High-Tech Yogurt Could Detect Disease

By | October 16, 2014

Nanoparticle-producing bacteria may simplify the diagnosis of cancer and other medical conditions.

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image: Obesity Complicates Colorectal Cancer

Obesity Complicates Colorectal Cancer

By | April 9, 2014

Study finds that prediagnosis obesity is predictive of poor prognosis, even among patients who have a molecular marker associated with better disease outcome.

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image: Bacteria’s Role in Bowel Cancer

Bacteria’s Role in Bowel Cancer

By | March 3, 2014

The development of serrated polyps depends on bacteria present in the gut, a mouse study shows.  

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image: Next Generation: Cancer Drug in Disguise

Next Generation: Cancer Drug in Disguise

By | November 5, 2013

Researchers develop a strategy for rendering a toxic drug harmless—until it encounters a pair of enzymes that signals cancer cells are nearby.

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