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tag dna nanotechnology ecology microbiology cell molecular biology

bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Building Nanoscale Structures with DNA
Arun Richard Chandrasekaran | Jul 16, 2017 | 10+ min read
The versatility of geometric shapes made from the nucleic acid are proving useful in a wide variety of fields from molecular computation to biology to medicine.
Epithelial cells and fungal spores are marked with fluorescent dyes. Cells have an irregular shape and are shown in green and blue colors. Spores are spherical in shape and are labeled green if they are surrounded by p11 protein. A protein in mature phagosomes is labeled violet.
Fungal Spores Hijack a Host Protein to Escape Death
Mariella Bodemeier Loayza Careaga, PhD | Jun 20, 2023 | 3 min read
Uncovering the components used by Aspergillus fumigatus to avoid intracellular destruction broadens our understanding of the mold’s pathogenesis. 
bacteria inside a biofilm
How Bacterial Communities Divvy up Duties
Holly Barker, PhD | Jun 1, 2023 | 10+ min read
Biofilms are home to millions of microbes, but disrupting their interactions could produce more effective antibiotics.
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
Bacteria and Humans Have Been Swapping DNA for Millennia
Kelly Robinson and Julie Dunning Hotopp | Oct 1, 2016 | 8 min read
Bacteria inhabit most tissues in the human body, and genes from some of these microbes have made their way to the human genome. Could this genetic transfer contribute to diseases such as cancer?
illustration of a mitochondrian inside a cell
Could Dad’s Mitochondrial DNA Benefit Hybrids?
Alejandra Manjarrez, PhD | Jan 20, 2022 | 7 min read
Studies have found that organisms can inherit mitochondria from male parents in rare instances, and both theoretical and experimental work hint that this biparental inheritance is more than just a fluke.
No Place to Hide
Claire Asher | May 31, 2017 | 7 min read
Environmental DNA is tracking down difficult-to-detect species, from rock snot in the U.S. to cave salamanders in Croatia.
When Stop Means Go
Ruth Williams | May 22, 2014 | 3 min read
A survey of trillions of base pairs of microbial DNA reveals a considerable degree of stop codon reassignment.
Opinion: Constrain Speculation to Protect the Integrity of Science
Mike Klymkowsky | Jun 18, 2018 | 4 min read
What we can know about biology before the last universal common ancestor is limited—and we should be circumspect in filling in the gaps.

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