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image: Designing Transition-State Inhibitors

Designing Transition-State Inhibitors

By | May 1, 2012

A transition-state mimic has the power to bind an enzyme at its tipping point as strongly as any available inhibitor and more strongly than most, preventing enzymatic activity. 

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image: Pure Pursuits

Pure Pursuits

By | May 1, 2012

Techniques for simpler, cheaper, and better antibody purification

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image: Tumor Turnabout

Tumor Turnabout

By | May 1, 2012

A cytokine involved in suppressing the immune system may actually activate it to kill cancer cells.

4 Comments

image: Freezing Time

Freezing Time

By | May 1, 2012

Targeting the briefest moment in chemistry may lead to an exceptionally strong new class of drugs.

15 Comments

image: Telomeres in Disease

Telomeres in Disease

By | May 1, 2012

Telomeres have been linked to numerous diseases over the years, but how exactly short telomeres cause diseases and how medicine can prevent telomere erosion are still up for debate.

16 Comments

image: Anti-inflammatory Factors Fight Bugs

Anti-inflammatory Factors Fight Bugs

By | April 25, 2012

A combination of antibiotics and the body’s own defensive metabolites clears bacterial infections faster than antibiotics alone.

4 Comments

image: Social Rank Affects Monkey Immunity

Social Rank Affects Monkey Immunity

By | April 11, 2012

In rhesus macaques, an individual's drop in the social hierarchy leads to overactive immune genes and, possibly, poor health.

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image: Ants Share Pathogens for Immunity

Ants Share Pathogens for Immunity

By | April 3, 2012

A new study shows that grooming by ants promotes colony-wide resistance to fungal infections by transferring small amounts of pathogen to nestmates.

8 Comments

image: Next Generation: Painless Vaccine Patch

Next Generation: Painless Vaccine Patch

By | April 2, 2012

Vaccination via tiny microneedles elicits a powerful immune response in the skin.

8 Comments

image: Are Cancer Stem Cells Ready for Prime Time?

Are Cancer Stem Cells Ready for Prime Time?

By | April 1, 2012

A flood of new discoveries has refined our definition of cancer stem cells. Now it’s up to human clinical trials to test if they can make a difference in patients.

48 Comments

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