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image: Battling the Bulge

Battling the Bulge

By | November 1, 2015

Weight-loss drugs that target newly characterized obesity-related receptors and pathways could finally offer truly effective fat control.

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image: Contributors

Contributors

By | November 1, 2015

Meet some of the people featured in the November 2015 issue of The Scientist.

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image: Fanning the Flames

Fanning the Flames

By | November 1, 2015

Obesity triggers a fatty acid synthesis pathway, which in turn helps drive T cell differentiation and inflammation.

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image: Weight's the Matter?

Weight's the Matter?

By | November 1, 2015

The causes and consequences of obesity are more complicated than we thought.  

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image: Breaking the Cancer-Obesity Link

Breaking the Cancer-Obesity Link

By , and | November 1, 2015

Obese people are at higher risk for developing cancer, have worse prognoses once diagnosed, and are often resistant to chemotherapy regimens. The question is, Why?

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image: Obesogens

Obesogens

By | November 1, 2015

Low doses of environmental chemicals can make animals gain weight. Whether they do the same to humans is a thorny issue.

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image: A Complex Disorder

A Complex Disorder

By , and | November 1, 2015

Factors that likely contribute to obesity include disruptions to intercellular signaling, increased inflammation, and changes to the gut microbiome.  

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image: Fat Factors

Fat Factors

By | November 1, 2015

A mouse's exposure to certain environmental chemicals can lead the animal—and its offspring and grandoffspring—to be overweight.

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image: Not Immune to Fat

Not Immune to Fat

By | November 1, 2015

The effect of a high-fat diet on murine T cells

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image: Evolution of the Penis

Evolution of the Penis

By | October 30, 2015

A phallus-less reptile goes through a developmental stage with external genitalia, suggesting a common origin for the organ among amniotes.

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