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bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Epigenetic Effects of Mom’s Diet
Emily Willingham | Apr 29, 2014 | 3 min read
Molecular markers of a mother’s nutrition around the time of conception can be found in her child’s DNA.
How Manipulating Rodent Memories Can Elucidate Neurological Function
Amber Dance | May 1, 2020 | 10+ min read
Strategies to make lab animals forget, remember, or experience false recollections probe how memory works, and may inspire treatments for neurological diseases.
The Role of Mom’s Microbes During Pregnancy
Carolyn A. Thomson and Kathy D. McCoy | Aug 1, 2021 | 10+ min read
Bacteria in the gut influence the production of antibodies and themselves secrete metabolites. In a pregnant woman, these compounds may influence immune development of her fetus.
An illustration of green bacteria floating above neutral-colored intestinal villi
The Inside Guide: The Gut Microbiome’s Role in Host Evolution
Catherine Offord | Jul 1, 2021 | 10+ min read
Bacteria that live in the digestive tracts of animals may influence the adaptive trajectories of their hosts.
Soybeans Hit Main Street
Barry Palevitz | Mar 19, 2000 | 8 min read
Once a favorite of Chinese emperors, tofu is now big time. From supermarkets to health food boutiques, diet-conscious Americans are buying soybeans, not just as tofu but in infant formula, soy milk, and soy burgers. Soy even has the Food and Drug Administration's seal of approval. Last October the FDA responded to a petition by Protein Technologies International, a St. Louis-based DuPont company specializing in soy products, by authorizing claims that soy protein is good for the heart. Acc
How Orphan Drugs Became a Highly Profitable Industry
Diana Kwon | May 1, 2018 | 10+ min read
Government incentives, advances in technology, and an army of patient advocates have spun a successful market—but abuses of the system and exorbitant prices could cause a backlash.
Notebook
Paul Smaglik | Nov 21, 1999 | 6 min read
Contents Pivotal pump Leptin limbo Clue to obesity Biotech Web site Helping hand Mapping malaria UCSD - Salk Program in Molecular Medicine HEART FAILURE RESCUE: A cross section of a mouse genetically engineered to develop heart failure (left) shows enlarged heart chambers and thin walls that are typical of the condition. A cross section from the same strain of mouse, but with the phospholamban gene (PLB) also missing, appears normal. PIVOTAL PUMP A biochemical calcium pump and the gene that con
Gut Microbes for Life
Ed Yong | Jul 4, 2013 | 3 min read
Most strains of gut microbes stay with us for decades, which may prove useful for tracking our health.
Transformer Cells in Diabetes
Ed Yong | Sep 13, 2012 | 3 min read
In diabetic mice, the cells of the pancreas don’t die, but rather revert to an earlier state incapable of producing the insulin the body needs.

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