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The Scientist

» clinical trials and immunology

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Some antibodies designed to eliminate the plaques prominent in Alzheimer’s disease can aggravate neuronal hyperactivity in mice.

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image: Microbes Play Role in Anti-Tumor Response

Microbes Play Role in Anti-Tumor Response

By | November 5, 2015

Gut microbiome composition can influence the effectiveness of cancer immunotherapy in mice.

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image: Ebola’s Immune Escape

Ebola’s Immune Escape

By | November 3, 2015

The virus can persist in several tissues where the immune system is less active. Researchers are working to better understand this phenomenon and how it can stall the clearing of Ebola in survivors.

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image: Fanning the Flames

Fanning the Flames

By | November 1, 2015

Obesity triggers a fatty acid synthesis pathway, which in turn helps drive T cell differentiation and inflammation.

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image: Not Immune to Fat

Not Immune to Fat

By | November 1, 2015

The effect of a high-fat diet on murine T cells

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image: Weak Support for Malaria Vaccine

Weak Support for Malaria Vaccine

By | October 27, 2015

The World Health Organization recommends more pilot trials.

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image: Latest in Heart Stem Cell Debate

Latest in Heart Stem Cell Debate

By | October 26, 2015

Given the right environment, cKit+ cells from the mouse heart can develop into new cardiac muscle, according to a study.

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image: B Cells Can Drive Inflammation in MS

B Cells Can Drive Inflammation in MS

By | October 21, 2015

Researchers identify a subset of proinflammatory cytokine-producing B cells that may spark multiple sclerosis-related inflammation.  

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image: Two-Faced Proteins May Tackle HIV Reservoirs

Two-Faced Proteins May Tackle HIV Reservoirs

By | October 21, 2015

Researchers design antibody-like proteins to awaken and destroy HIV holdouts.

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image: Duke Cardiologist Tapped to Lead FDA

Duke Cardiologist Tapped to Lead FDA

By | September 17, 2015

The Obama administration has nominated Robert Califf, a researcher who conducted large clinical trials, as the next person to head the country’s drug approval agency.

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