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image: One Receptor, Two Ligands, Different Responses

One Receptor, Two Ligands, Different Responses

By | August 31, 2016

Host and bacterial ligands that interact with the same cell-surface receptor induce different activities in human macrophages. 

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image: One Antigen Receptor Induces Two T cell Types

One Antigen Receptor Induces Two T cell Types

By | August 26, 2016

Precursor T cells bearing the same antigen receptor adopt two different fates in mice.

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image: Macrophages Respond to Liver Injury

Macrophages Respond to Liver Injury

By | August 1, 2016

In mice, immune cells from the body cavity surrounding organs arrive at the site of damage to chew up the nuclei of dead cells.

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image: Newly Discovered Emergency Responders to Liver Damage

Newly Discovered Emergency Responders to Liver Damage

By | August 1, 2016

Immune cells called macrophages from the peritoneal cavity of mice migrate to injured livers and aid in repair.

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image: CRISPR Therapy to Enter Trials

CRISPR Therapy to Enter Trials

By | July 25, 2016

Researchers in China will use the CRISPR-Cas9 system to edit T cells extracted from patients with cancer before those cells are returned to the body to target malignant ones.

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Juno Therapeutics asks the US Food and Drug Administration for permission to restart the CAR-T experiments without chemotherapy.

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image: Composite Endpoints in Clinical Trials

Composite Endpoints in Clinical Trials

By | July 1, 2016

There’s a right way and a wrong way to boost the statistical sensitivity of this type of clinical studies.

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image: Immune Cell–Stem Cell Cooperation

Immune Cell–Stem Cell Cooperation

By , , and | July 1, 2016

Understanding interactions between the immune system and stem cells could pave the way for successful stem cell–based regenerative therapies.

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image: Immune Cells' Roles in Tissue Maintenance and Repair

Immune Cells' Roles in Tissue Maintenance and Repair

By , , and | July 1, 2016

The cells of the mammalian immune system do more than just fight off pathogens; they are also important players in stem cell function and are thus crucial for maintaining homeostasis and recovering from injury.

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image: Vaccines Protect Mice Against Zika Infection

Vaccines Protect Mice Against Zika Infection

By | June 29, 2016

Two different vaccines confer complete immunity for two months, researchers report.

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