With deep learning methods revolutionizing life sciences, researchers bet on de novo proteins and cell mapping models to deliver customized precision medicines.

Using precision genome editing to treat or prevent human disease may require several leaps of faith.

Haydeh Payami helped uncover the genetic basis of Parkinson’s disease. Now, she hopes to find new ways to treat the disease by studying the gut microbiome.

Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.

Traditional gene therapy is built on a simple premise: If the absence of a gene product causes disease, then adding the missing gene will cure it.

Paola Arlotta seeks to understand the complex symphony of brain development in vitro by using organoid models.

At first blush, do-it-yourself clinical trials seem pointless and reckless. But a deeper truth pervades the research and the patients who drive it forward.

Researchers at the RIKEN Center for Developmental Biology will treat the first patient in its clinical trial testing an induced pluripotent stem cell-based treatment for age-related macular degeneration.

Pradipta Ghosh has plans to revolutionize the drug discovery pipeline.

The field is young, but predicting antigens produced by patients’ malignant cells could yield successful treatments for individuals with a range of cancer types.