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image: The Challenges of Rare-Disease Research

The Challenges of Rare-Disease Research

By | September 1, 2016

With few resources and hesitant investors, basic scientists must rely on clinicians, patient advocates, and their own keen eye for biological connections.

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image: Odor, Taste, and Light Receptors in Unusual Locations

Odor, Taste, and Light Receptors in Unusual Locations

By | September 1, 2016

From the gut and airways to the blood, muscle, and skin, diverse sensory receptors are doing unconventional things.

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image: Proprioception: The Sense Within

Proprioception: The Sense Within

By and | September 1, 2016

Knowing where our bodies are in space is critical for the control of our movements and for our sense of self.

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image: What Sensory Receptors Do Outside of Sense Organs

What Sensory Receptors Do Outside of Sense Organs

By | September 1, 2016

Odor, taste, and light receptors are present in many different parts of the body, and they have surprisingly diverse functions.

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image: Immunotherapy for Alzheimer’s Disease Shows Promise

Immunotherapy for Alzheimer’s Disease Shows Promise

By | August 31, 2016

Biogen’s aducanumab reduces amyloid-β plaques in a dose-dependent manner, according to interim results of a Phase 1b clinical trial.

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image: One Receptor, Two Ligands, Different Responses

One Receptor, Two Ligands, Different Responses

By | August 31, 2016

Host and bacterial ligands that interact with the same cell-surface receptor induce different activities in human macrophages. 

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image: One Antigen Receptor Induces Two T cell Types

One Antigen Receptor Induces Two T cell Types

By | August 26, 2016

Precursor T cells bearing the same antigen receptor adopt two different fates in mice.

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Disrupting the light/dark cycles of pregnant mice, researchers observe detrimental effects in the mouths of the animals’ pups.

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image: Wanted: Transcriptional Regulators

Wanted: Transcriptional Regulators

By | August 1, 2016

Researchers have designed a screen to find unique molecules, called riboswitches, that determine whether transcription will proceed.

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image: CRISPR Therapy to Enter Trials

CRISPR Therapy to Enter Trials

By | July 25, 2016

Researchers in China will use the CRISPR-Cas9 system to edit T cells extracted from patients with cancer before those cells are returned to the body to target malignant ones.

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