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image: Cell Lines Gain Cancer-Related Mutations

Cell Lines Gain Cancer-Related Mutations

By | April 27, 2017

A screen of human embryonic stem cell lines finds several that accumulated changes in the gene TP53, including aberrations commonly seen in cancer.

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The lungs of extremely premature lambs supported in a closed, sterile environment that enables fluid-based gas exchange grow and develop normally, researchers report.

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image: Image of the Day: Stop Signals

Image of the Day: Stop Signals

By | April 17, 2017

Transcytosis, suppression of vesicle traffic across cells, helps reduce permeability in the blood-retinal barrier during development.

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A mouse study reveals a causal link between changes in intestinal microbiota and increasing inflammation as the rodents age.

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Mice exposed to low doses of penicillin in utero or as young pups exhibited long-term behavioral differences not seen in their non-exposed counterparts, according to a study.

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Recolonizing middle-aged animals with bacteria from younger ones kept killifish alive longer than usual, researchers report.

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image: DNA-Based Zika Vaccine Reaches Phase 2

DNA-Based Zika Vaccine Reaches Phase 2

By | April 4, 2017

An NIAID-sponsored clinical trial advances beyond safety testing.

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At the annual American Association for Cancer Research meeting, researchers discuss the importance of understanding the epigenetic contributors to cancer progression and treatment response.

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image: In Certain Social Bees, Gut Microbiomes Follow Phylogeny

In Certain Social Bees, Gut Microbiomes Follow Phylogeny

By | March 29, 2017

Corbiculate bees and their gut-dwelling microbes have been coevolving since the social species evolved from their solitary ancestors around 80 million years ago, scientists suggest. 

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image: Rethinking a Cancer Drug Target

Rethinking a Cancer Drug Target

By | March 26, 2017

The results of a CRISPR-Cas9 study suggest that MELK—a protein thought to play a critical role in cancer—is not necessary for cancer cell survival.

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