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image: Epigenetic Cancer Therapy Clears Phase I

Epigenetic Cancer Therapy Clears Phase I

By | April 7, 2014

Investigational drug that inhibits proteins involved with epigenetic regulation shows activity against certain blood cancers in an early-stage clinical trial.

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image: Making Better Mesenchymal Stem Cells

Making Better Mesenchymal Stem Cells

By | March 27, 2014

Scientists generate a new crop of stem cells that show therapeutic potential in mouse models of autoimmune diseases.

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image: Saving Failing Hearts

Saving Failing Hearts

By | March 12, 2014

Inhibiting a small regulatory RNA appears to improve cardiac function in mice with surgically induced heart problems.

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image: FDA Considers Three-Way Babies

FDA Considers Three-Way Babies

By | February 26, 2014

The agency is soliciting opinions on a new technology that has the potential to circumvent mitochondrial diseases by producing embryos using DNA from three people.

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image: Opinion: Translational Biotechnology

Opinion: Translational Biotechnology

By | February 17, 2014

Regulators must consider both the promise and potential pitfalls of new technologies when determining whether to move them into clinical trials.

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image: Unauthorized HIV Trial Leader Fined

Unauthorized HIV Trial Leader Fined

By | February 3, 2014

A Spanish researcher faces a penalty after conducting a study for which he never obtained proper approvals or insurance.

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image: J&J to Share Trial Data

J&J to Share Trial Data

By | January 31, 2014

The pharmaceutical giant teams up with Yale University to make raw clinical data available to researchers.

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image: Stem Cell Trials in Peril?

Stem Cell Trials in Peril?

By | January 27, 2014

The only US firm with an ongoing embryonic stem cell therapy clinical trial is in financial and legal hot water.

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image: Inconsistent Evidence

Inconsistent Evidence

By | January 22, 2014

More than a third of US drug approvals are based on a single large clinical trial, while others require more in-depth study, according to a new report.

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image: Next Generation: Cancer Cell Protein Profiling

Next Generation: Cancer Cell Protein Profiling

By | January 15, 2014

Antibody barcoding allows scientists and clinicians to analyze protein expression in small amounts of cancer tissue.

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