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image: Stem Cell Trial Data Mostly Go Unpublished

Stem Cell Trial Data Mostly Go Unpublished

By | May 5, 2017

Less than half of completed stem cell studies in humans are published in peer-reviewed journals, according to an analysis of regenerative medicine trials. 

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image: Cell Lines Gain Cancer-Related Mutations

Cell Lines Gain Cancer-Related Mutations

By | April 27, 2017

A screen of human embryonic stem cell lines finds several that accumulated changes in the gene TP53, including aberrations commonly seen in cancer.

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image: DNA-Based Zika Vaccine Reaches Phase 2

DNA-Based Zika Vaccine Reaches Phase 2

By | April 4, 2017

An NIAID-sponsored clinical trial advances beyond safety testing.

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At the annual American Association for Cancer Research meeting, researchers discuss the importance of understanding the epigenetic contributors to cancer progression and treatment response.

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image: Rethinking a Cancer Drug Target

Rethinking a Cancer Drug Target

By | March 26, 2017

The results of a CRISPR-Cas9 study suggest that MELK—a protein thought to play a critical role in cancer—is not necessary for cancer cell survival.

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image: Women Lose Vision After Stem Cell Treatment

Women Lose Vision After Stem Cell Treatment

By | March 17, 2017

The adipose-derived cells were injected into the patients’ eyes to treat age-related macular degeneration. 

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image: Kite’s CAR T-Cell Therapy Success

Kite’s CAR T-Cell Therapy Success

By | March 1, 2017

More than one-third of lymphoma patients in a Phase 2 trial were clear of disease at six months, and no new safety concerns arose since the company’s three-month follow up.

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image: HIV Vaccines May Help Tamp Down Virus

HIV Vaccines May Help Tamp Down Virus

By | February 24, 2017

A fraction of HIV patients in a small, uncontrolled study were able to stop antiretroviral therapy after receiving the immune boosters.

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image: Regulators OK Clinical Trials Using Donor Stem Cells

Regulators OK Clinical Trials Using Donor Stem Cells

By | February 6, 2017

Japanese health officials approve human experiments to treat macular degeneration with a cell therapy derived from induced pluripotent stem cells.

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image: Opinion: Improving FDA Evaluations Without Jeopardizing Safety and Efficacy

Opinion: Improving FDA Evaluations Without Jeopardizing Safety and Efficacy

By | February 1, 2017

What can be done to lower development costs and drug prices?

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