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tag germ cells disease medicine evolution developmental biology

Stem Cell Trial for Eye Disease Commences
Jef Akst | Sep 12, 2014 | 2 min read
Researchers at the RIKEN Center for Developmental Biology will treat the first patient in its clinical trial testing an induced pluripotent stem cell-based treatment for age-related macular degeneration.
Image of the tissue surrounding a pancreatic tumor thickening and scarring.
How Pancreas Injuries Can Cause Cancer in Mice
Dan Robitzski | Nov 9, 2021 | 4 min read
A key mutation turns healing cells into cancer promoters.
Guts and Glory
Anna Azvolinsky | Apr 1, 2016 | 9 min read
An open mind and collaborative spirit have taken Hans Clevers on a journey from medicine to developmental biology, gastroenterology, cancer, and stem cells.
Tissue Engineering and Regenerative Medicine: A New Frontier in Repairing Organ Damage
Brush Up: Tissue Engineering and Regenerative Medicine
Jennifer Zieba, PhD | Oct 17, 2022 | 4 min read
A new frontier in repairing organ damage
3d rendered medically accurate illustration of a human embryo anatomy
The Ephemeral Life of the Placenta
Danielle Gerhard, PhD | Dec 4, 2023 | 10+ min read
Recent advances in modeling the human placenta, the least understood organ, may inform placental disorders like preeclampsia.
a trio of infant mice, two brown mice on the ends and one white mouse in the middle
Mice Pass Epigenetic Tweaks to Pups
Katherine Irving | Feb 17, 2023 | 5 min read
An engineered methylation pattern persisted for four generations of mice, demonstrating transgenerational epigenetic inheritance can occur in mammals.
Why, Oh Y?
Jef Akst | Jan 1, 2015 | 9 min read
A toothpick and a bit of chance shaped David Page’s career, which he has dedicated to understanding the mammalian Y chromosome and fetal germ cell development.
How Groups of Cells Cooperate to Build Organs and Organisms
Michael Levin | Sep 1, 2020 | 10+ min read
Understanding biology’s software—the rules that enable great plasticity in how cell collectives generate reliable anatomies—is key to advancing tissue engineering and regenerative medicine.
Are Phages Overlooked Mediators of Health and Disease?
Catherine Offord | Feb 1, 2021 | 10+ min read
Bacteria-infecting viruses affect the composition and behavior of microbes in the mammalian gut—and perhaps influence human biology.
Conceptual image showing molecules making up a brain shape
The Noncoding Regulators of the Brain
Christie Wilcox, PhD | Sep 12, 2022 | 10+ min read
Noncoding RNAs are proving to be critical players in the evolution of brain anatomy and cognitive complexity.

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