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tag drug development microbiology evolution genetics genomics

Individual bacterial transcriptomes each plotted as a single point create a ring-shaped structure.
Rapidly Dividing Bacteria Coordinate Gene Expression and Replication
Kamal Nahas, PhD | Mar 15, 2024 | 4 min read
E. coli divides faster than it can replicate its genome, while simultaneously expressing its genes. Scientists recently revealed the intricate molecular coordination that makes this possible.
bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
illustration of virus particles and DNA strands
Ancient Viral DNA Plays a Role in Human Disease and Development
Aidan Burn, The Conversation | Oct 19, 2022 | 4 min read
Viral remnants make up 8 percent of the human genome, and a new study finds that these sequences are still active in healthy people.
800x560-october-20-2021
Keeping Pace With SARS-CoV-2 Evolution
The Scientist Creative Services Team in collaboration with Thermo Fisher Scientific | Sep 29, 2021 | 1 min read
Eugene Koonin and Eric Niederkofler discuss novel technologies to improve viral mutation surveillance.
3D illustration of greenish-brown rod-shaped bacteria.
A Novel Molecule to Tackle Drug-Resistant Bugs
Aparna Nathan, PhD | Feb 12, 2024 | 4 min read
A new antibiotic is the first to block a critical transport mechanism in drug-resistant bacteria.
Bugs as Drugs to Boost Cancer Therapy
Danielle Gerhard, PhD | Jan 18, 2024 | 7 min read
Bioengineered bacteria sneak past solid tumor defenses to guide CAR T cells’ attacks.
Different colored cartoon viruses entering holes in a cartoon of a human brain.
A Journey Into the Brain
Danielle Gerhard, PhD | Mar 22, 2024 | 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
A bat flying in a dark cave
Turning on the Bat Signal
Hannah Thomasy, PhD | Mar 15, 2024 | 10+ min read
Scientists around the world investigate how bat immune systems cope with viral attacks and how this information could be used to keep humans safe.
Green leaves in a row with varied degrees of black spots on a black background.
A New Drug Fixes a Leak Caused by Bacteria
Kamal Nahas, PhD | Nov 8, 2023 | 5 min read
Researchers discovered how virulent bacterial proteins leech nutrients from plant cells, leading to a potential treatment for diseased crops.
Electric Bacteria: Out of the Darkness and into the Light
Hannah Thomasy, PhD | Feb 29, 2024 | 6 min read
Once obscure mud microbes inspire a new generation of living electronics.

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