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» drug development and immunology

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image: Size Matters to Industry

Size Matters to Industry

By | April 11, 2012

Large molecules are more likely to make it to market these days than small molecules, according to new reports.

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image: Social Rank Affects Monkey Immunity

Social Rank Affects Monkey Immunity

By | April 11, 2012

In rhesus macaques, an individual's drop in the social hierarchy leads to overactive immune genes and, possibly, poor health.

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image: Ants Share Pathogens for Immunity

Ants Share Pathogens for Immunity

By | April 3, 2012

A new study shows that grooming by ants promotes colony-wide resistance to fungal infections by transferring small amounts of pathogen to nestmates.

8 Comments

image: Next Generation: Painless Vaccine Patch

Next Generation: Painless Vaccine Patch

By | April 2, 2012

Vaccination via tiny microneedles elicits a powerful immune response in the skin.

8 Comments

image: Obesity Drugs in Check

Obesity Drugs in Check

By | April 2, 2012

The FDA may require weight-loss drugs to undergo clinical trials to see if they pose a risk of heart attack.

2 Comments

image: Failed Drugs Expose Preclinical Blunders

Failed Drugs Expose Preclinical Blunders

By | March 30, 2012

Once a promising cancer treatment, the failure of PARP inhibitors in the clinic may be due to flawed preclinical studies.

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image: Collecting Cancer Data

Collecting Cancer Data

By | March 29, 2012

Two new cancer cell line databases bursting with genomic and drug profiling data may help researchers identify drug targets.

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image: Molecular Blueprints

Molecular Blueprints

By | March 27, 2012

Check out the latest crop of high-resolution structures and how they inform biological function.

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image: Let Them Eat Dirt

Let Them Eat Dirt

By | March 22, 2012

Early exposure to microbes shapes the mammalian immune system by subduing inflammatory T cells.

28 Comments

image: Immune Role in Brain Disorder?

Immune Role in Brain Disorder?

By | March 19, 2012

Replacing immune cells in a mouse model of Rett syndrome, a developmental brain disorder, improved symptoms, suggesting a new target for treatment.

2 Comments

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