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» drug development and immunology

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image: Birth of the Skin Microbiome

Birth of the Skin Microbiome

By | November 17, 2015

The immune system tolerates the colonization of commensal bacteria on the skin with the aid of regulatory T cells during the first few weeks of life, a mouse study shows.

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image: Clinical Trial Data Underreported: Study

Clinical Trial Data Underreported: Study

By | November 16, 2015

One-third of the human experiments for approved drugs failed transparency requirements.

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image: Breaching the Blood-Brain Barrier

Breaching the Blood-Brain Barrier

By | November 11, 2015

Researchers deliver cancer-fighting drugs to a patient’s brain via the bloodstream, penetrating the blood-brain barrier for the first time.

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image: Microbes Play Role in Anti-Tumor Response

Microbes Play Role in Anti-Tumor Response

By | November 5, 2015

Gut microbiome composition can influence the effectiveness of cancer immunotherapy in mice.

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image: Ebola’s Immune Escape

Ebola’s Immune Escape

By | November 3, 2015

The virus can persist in several tissues where the immune system is less active. Researchers are working to better understand this phenomenon and how it can stall the clearing of Ebola in survivors.

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image: Battling the Bulge

Battling the Bulge

By | November 1, 2015

Weight-loss drugs that target newly characterized obesity-related receptors and pathways could finally offer truly effective fat control.

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image: Fanning the Flames

Fanning the Flames

By | November 1, 2015

Obesity triggers a fatty acid synthesis pathway, which in turn helps drive T cell differentiation and inflammation.

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image: Not Immune to Fat

Not Immune to Fat

By | November 1, 2015

The effect of a high-fat diet on murine T cells

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image: Weak Support for Malaria Vaccine

Weak Support for Malaria Vaccine

By | October 27, 2015

The World Health Organization recommends more pilot trials.

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image: B Cells Can Drive Inflammation in MS

B Cells Can Drive Inflammation in MS

By | October 21, 2015

Researchers identify a subset of proinflammatory cytokine-producing B cells that may spark multiple sclerosis-related inflammation.  

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