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image: Failed Drugs Expose Preclinical Blunders

Failed Drugs Expose Preclinical Blunders

By | March 30, 2012

Once a promising cancer treatment, the failure of PARP inhibitors in the clinic may be due to flawed preclinical studies.

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image: Collecting Cancer Data

Collecting Cancer Data

By | March 29, 2012

Two new cancer cell line databases bursting with genomic and drug profiling data may help researchers identify drug targets.

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image: Molecular Blueprints

Molecular Blueprints

By | March 27, 2012

Check out the latest crop of high-resolution structures and how they inform biological function.

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image: Baldness Genes Discovered?

Baldness Genes Discovered?

By | March 26, 2012

Researchers say they've found key molecular clues to a problem that plagues 80 percent of men.

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image: Debate over RNA Transcription

Debate over RNA Transcription

By | March 19, 2012

Researchers question earlier findings of a new mechanism for gene regulation.

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image: A FASTer FDA?

A FASTer FDA?

By | March 19, 2012

A new bill recently debated in the US Congress seeks to streamline the approval process for drugs.

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image: Designer Aspirin Fights Cancer

Designer Aspirin Fights Cancer

By | March 5, 2012

Early experiments show that a hybrid form of the common pain reliever can effectively inhibit the growth of many tumor types.

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image: What it Takes to Develop Better Drugs for Kids

What it Takes to Develop Better Drugs for Kids

By | March 1, 2012

Over the past 15 years, new laws and regulations in the United States and the European Union have expanded to require the inclusion of pediatric patients in clinical drug trials.  

2 Comments

image: Are the Kids Alright?

Are the Kids Alright?

By | March 1, 2012

Two key pieces of legislation, enacted to spur drugmakers into testing pharmaceutical products in children, are up for reauthorization in the US Congress this October. Have they done their jobs?

6 Comments

image: David Sabatini: Demystifying mTOR

David Sabatini: Demystifying mTOR

By | March 1, 2012

Principal Investigator, Whitehead Institute for Biomedical Research. Associate Professor, Department of Biology, Massachusetts Institute of Technology. Age: 44

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