The FDA may require weight-loss drugs to undergo clinical trials to see if they pose a risk of heart attack.
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During development, the cells of an embryo change their pattern of gene expression, which allows them to detach from their original location and migrate to another part of the embryo, where the pattern changes again to allow formation of a new organ.
A flood of new discoveries has refined our definition of cancer stem cells. Now it’s up to human clinical trials to test if they can make a difference in patients.
Once a promising cancer treatment, the failure of PARP inhibitors in the clinic may be due to flawed preclinical studies.
Two new cancer cell line databases bursting with genomic and drug profiling data may help researchers identify drug targets.
Check out the latest crop of high-resolution structures and how they inform biological function.
A new bill recently debated in the US Congress seeks to streamline the approval process for drugs.
Over the past 15 years, new laws and regulations in the United States and the European Union have expanded to require the inclusion of pediatric patients in clinical drug trials. Before these laws were enacted, the US Food and Drug Administration (F
Two key pieces of legislation, enacted to spur drugmakers into testing pharmaceutical products in children, are up for reauthorization in the US Congress this October. Have they done their jobs?
A lot changes in a child’s body over the course of development, and not all changes occur linearly: gene expression can fluctuate, and organs can perform different functions on the way to their final purpose in the body. Here are some of the key deve
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