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image: Fatal-Disease Drug in Limbo

Fatal-Disease Drug in Limbo

By | November 25, 2015

A panel of experts advised the US Food and Drug Administration that BioMarin Pharmaceutical has not demonstrated efficacy of its new drug for Duchenne muscular dystrophy.

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image: Opinion: Translation Nation

Opinion: Translation Nation

By | November 18, 2015

What’s in store for commercialization grants at the Canadian Institutes of Health Research?

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image: Birth of the Skin Microbiome

Birth of the Skin Microbiome

By | November 17, 2015

The immune system tolerates the colonization of commensal bacteria on the skin with the aid of regulatory T cells during the first few weeks of life, a mouse study shows.

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image: Clinical Trial Data Underreported: Study

Clinical Trial Data Underreported: Study

By | November 16, 2015

One-third of the human experiments for approved drugs failed transparency requirements.

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image: Breaching the Blood-Brain Barrier

Breaching the Blood-Brain Barrier

By | November 11, 2015

Researchers deliver cancer-fighting drugs to a patient’s brain via the bloodstream, penetrating the blood-brain barrier for the first time.

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image: Microbes Play Role in Anti-Tumor Response

Microbes Play Role in Anti-Tumor Response

By | November 5, 2015

Gut microbiome composition can influence the effectiveness of cancer immunotherapy in mice.

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image: Ebola’s Immune Escape

Ebola’s Immune Escape

By | November 3, 2015

The virus can persist in several tissues where the immune system is less active. Researchers are working to better understand this phenomenon and how it can stall the clearing of Ebola in survivors.

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image: Battling the Bulge

Battling the Bulge

By | November 1, 2015

Weight-loss drugs that target newly characterized obesity-related receptors and pathways could finally offer truly effective fat control.

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image: Fanning the Flames

Fanning the Flames

By | November 1, 2015

Obesity triggers a fatty acid synthesis pathway, which in turn helps drive T cell differentiation and inflammation.

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image: Not Immune to Fat

Not Immune to Fat

By | November 1, 2015

The effect of a high-fat diet on murine T cells

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