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image: Centennial <em>Shigella</em>

Centennial Shigella

By | February 1, 2015

A strain of the dysentery-causing bacterium isolated in 1915 tells the story of a young soldier who died of the disease in the early days of World War I.

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image: Lazarus Drugs

Lazarus Drugs

By | February 1, 2015

While some drugs sail through development, others suffer setbacks, including FDA rejections, before reaching the market.  

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image: Nibbled? No Problem

Nibbled? No Problem

By | February 1, 2015

Making extra copies of their genomes allows some plants to better withstand damage.

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image: Screening Goes In Silico

Screening Goes In Silico

By | February 1, 2015

Computational tools take some of the cost—and guesswork—out of drug discovery.

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image: Contributors

Contributors

By | February 1, 2015

Meet some of the people featured in the February 2015 issue of The Scientist.

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image: How Transposons Shaped Pregnancy

How Transposons Shaped Pregnancy

By | January 29, 2015

A mass migration of mobile regulatory elements increased the expression of thousands of genes in the uterus during the evolution of pregnancy.

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image: Drug Stimulates Brown Fat

Drug Stimulates Brown Fat

By | January 28, 2015

A small study finds that an approved medication increases metabolic rate and the activity of thermogenic brown fat in men.

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image: America’s First Pooches

America’s First Pooches

By | January 27, 2015

Study of ancient dog DNA sheds light on early Americans’ relationships with their pets.

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image: Reducing Gene Therapy-Related Risk

Reducing Gene Therapy-Related Risk

By | January 22, 2015

In a mouse model of a rare disease, scientists have figured out how to reduce the elevated cancer risk tied to a gene therapy treatment.

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image: GMO “Kill Switches”

GMO “Kill Switches”

By | January 21, 2015

Scientists design bacteria reliant upon synthetic amino acids to contain genetically modified organisms.

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