New work on salicylate, a natural component of aspirin, suggests that activation of the energy-sensing AMP kinase may underlie some of aspirin’s health benefits.
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A novel antibody with a powerful affinity for cocaine shows promise in reversing the deadly effects of an overdose.
Francis Collins says pharmaceutical companies should help bridge the gap between basic science and applications with old drug compounds.
Large molecules are more likely to make it to market these days than small molecules, according to new reports.
The FDA may require weight-loss drugs to undergo clinical trials to see if they pose a risk of heart attack.
Once a promising cancer treatment, the failure of PARP inhibitors in the clinic may be due to flawed preclinical studies.
Two new cancer cell line databases bursting with genomic and drug profiling data may help researchers identify drug targets.
Check out the latest crop of high-resolution structures and how they inform biological function.
A new bill recently debated in the US Congress seeks to streamline the approval process for drugs.
Over the past 15 years, new laws and regulations in the United States and the European Union have expanded to require the inclusion of pediatric patients in clinical drug trials. Before these laws were enacted, the US Food and Drug Administration (F
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