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tag policy genetics genomics

2022 Top 10 Innovations 
2022 Top 10 Innovations
The Scientist | Dec 12, 2022 | 10+ min read
This year’s crop of winning products features many with a clinical focus and others that represent significant advances in sequencing, single-cell analysis, and more.
Controversy Mounts Over Gene Patenting Policy
Scott Veggeberg | Apr 26, 1992 | 5 min read
Scientists in industry and academia foresee trouble as NIH persists in claiming ownership over partial sequences Date: April 27, 1992 The reviews from the scientific community remain mostly negative over the National Institutes of Health's patent application for a total of 2,722 partial human gene sequences. Academic researchers, who say they are mostly unaffected by the patenting process, nevertheless are appalled; and while some in the commercial sector of the biotech community now believe
Toward a “Clickable Plant”
Jane Salodof Macneil | Feb 15, 2004 | 9 min read
By conscious design, plant genomics initiatives have devoted initial resources to new technology development. Part of that money went to developing functional genomics approaches, and part to new sequencing technologies.
Sequencing Stakes: Celera Genomics Carves Its Niche
Ricki Lewis | Jul 18, 1999 | 8 min read
J. Craig Venter is no stranger to contradiction and controversy. He seems to thrive on it. In 1991, when the National Institutes of Health was haggling over patenting expressed sequence tags (ESTs)--a shortcut to identifying protein-encoding genes--Venter the inventor accepted a private offer to found The Institute for Genomic Research (TIGR) in Rockville, Md. TIGR would discover ESTs and give most of them to a commercial sibling, Human Genome Sciences (HGS), to market. ESTs are now a standard
How Orphan Drugs Became a Highly Profitable Industry
Diana Kwon | May 1, 2018 | 10+ min read
Government incentives, advances in technology, and an army of patient advocates have spun a successful market—but abuses of the system and exorbitant prices could cause a backlash.
Privatizing the Human Genome?
Paul Smaglik | Jun 7, 1998 | 10 min read
Principals behind joint-venture proposal and public effort seek to define relationships A private effort to sequence the human genome four years ahead of the Human Genome Project's 2005 goal could either compete directly with the federal project or meld seamlessly with it. Before any relationship between the two efforts becomes formalized, scientists and federal officials involved with the Human Genome Project must determine whether the private approach will work, who will own the data, how qu
Researchers Blast Open Pathogen Genome
Barry Palevitz | Aug 18, 2002 | 6 min read
Image: Courtesy of Tim Elkins BRUTE FORCE: Remnant of an appressorium formed on Mylar. The appressorium produced a peg-like extension that penetrated the film, leaving a round hole. (Reprinted with permission, Annual Review of Microbiology, 50:491-512, 1996.) "The Lord shall smite thee with a consumption, and with a fever, and with an inflammation, and with an extreme burning, and with the sword, and with BLASTING, and with mildew; and they shall pursue thee until thou perish." Deuteronom
Planning the Future of Plant Genomics
Eugene Russo | Jul 21, 2002 | 5 min read
Image: Courtesy of National Sciences Foundation Arabidopsis Plant genomics researchers stand at a crossroads. Behind them are the completed genome sequences of rice1 and the model mustard plant Arabidopsis thaliana.2 Now, armed with insights gained from both plant and animal sequencing projects, plant biologists must decide how to proceed with future sequencing, proteomics, and functional genomics endeavors--and how to allot precious basic research dollars while, at the same time, keeping
Will Genomics Spoil Gene Ownership?
Douglas Steinberg | Sep 3, 2000 | 8 min read
Consider a scenario for the year 2002: Using commercially available software, bioprospector "Craig Collins" spends a day scavenging the Human Genome Project (HGP) database for the alternatively spliced genes prized by Wall Street. He enters the sequences of several candidate genes into a software package that prints out the likely functions of their protein products. One protein looks like it could be pharmaceutical paydirt, so he isolates the corresponding cDNA, inserts it into a vector, then
News Notes
Eugene Russo | Dec 10, 2000 | 3 min read
Next Up for Gene Sequencing: Zebrafish Sequencing of the zebrafish genome will aid annotation of the human genome and facilitate gene identification. Already a widely used genetics animal model, the zebrafish will soon join the ranks of organisms whose genomes have been sequenced, thus boosting the popular aquarium pet's research value even more. The Sanger Centre of Cambridge, U.K., announced on Nov. 21 that it would head zebrafish-sequencing efforts, scheduled to begin in February or March o

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