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tag toxoplasma gondii cell molecular biology

Illustration of clear cells with orange nuclei, Toxoplasma gondii, on colorful background
Turning Toxoplasma Against Cancer
Annie Melchor | Jan 3, 2022 | 9 min read
Several research groups have found that Toxoplasma gondii infection can ramp up antitumor immune responses in mice. Can the single-cell parasite be used to develop safe treatments for humans?
PAPERS TO WATCH
The Scientist Staff | Jul 1, 2006 | 1 min read
I. Coppens et al.," Toxoplasma gondii sequesters lysosomes from mammalian hosts in the vacuolar space," Cell , 125:261-74, April 21, 2006. This outstanding paper shows that the intracellular protozoan Toxoplasma gondii exploits host microtubules to recruit and sequester host lysosomes into the parasitophorous vacuole. Through this process, the parasite gains access to host organelles that can provide a source of low-molecular-weight nu
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Microbiology Meets Machine Learning
Ruth Williams | May 1, 2019 | 2 min read
Artificially intelligent software has human-like ability to analyze host-pathogen interactions in microscopy images.
RNA Arms Race
Mohamed-Ali Hakimi and Robert M?nard | Aug 1, 2010 | 4 min read
Mohamed-Ali Hakimi and Robert Ménard RNA Arms Race Do parasites use their own microRNAs to hijack host cell pathways? Red blood cells infected with the Plasmodium falciparum parasite. GARY D. GAUGLER / PHOTO RESEARCHERS, INC. RNA silencing, which fine tunes up to 30% of genome during development,1 also plays a major role in innate antiviral and antibacterial defenses in plants, insects, and animals. But
Parasitologist, Reprogrammed: A Profile of David Roos
Anna Azvolinsky | Mar 1, 2018 | 8 min read
After discovering a novel organelle found in protozoan parasites, the University of Pennsylvania’s Roos created a widely used eukaryotic pathogen database.
What Neurobiology Can Tell Us About Suicide
Catherine Offord | Jan 13, 2020 | 10+ min read
The biochemical mechanisms in the brain underlying suicidal behavior are beginning to come to light, and researchers hope they could one day lead to better treatment and prevention strategies.
Animal Mind Control
Jef Akst | Jan 1, 2012 | 10+ min read
Examples of parasites that manipulate the behavior of their hosts are not hard to come by, but scientists have only recently begun to understand how they induce such dramatic changes.
The 2007 Life Sciences Industry Awards
Andrea Gawrylewski, Bob Grant, and Manasee Wagh | Apr 16, 2007 | 10+ min read
Saluting the winners: Customization, value, and customer service is the name of the game
Life Science Industry Awards 2007
Andrea Gawrylewski, Bob Grant, and Manasee Wagh | May 1, 2007 | 10+ min read
Life Science Industry Awards 2007 Saluting the winners: Customization, value, and customer service is the name of the game. By Andrea Gawrylewski, Bob Grant, and Manasee Wagh Although biomedical companies in search of new drugs often seem to grab all the headlines, anyone working in bioscience research and drug development knows that none of their advances would be possible without the life science industry that creates the rea
The Hopes and Realities of the Plasmodium falciparum Genome
Brendan Maher | Nov 24, 2002 | 6 min read
Photo: Courtesy of the World Health Organization, P. Virot THE REALITY OF ETHIOPIA: Trying to survive malaria in Ethiopia, on Africa's east coast. In 1998, Ethiopia's infant mortality rate was 116 per 1,000 live births (WHO) compared to 7.2 per 1000 in the US (CDC). Sequencing a 23-megabase genome hardly sounds like a triumph--that's just twice the size of an average yeast genome and one-hundredth of the human genome. Yet, there was cause for celebration after a high-profile team of coll

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