genetics & genomics

Neurons within a person’s brain exhibit striking variations in DNA copy number.

Whole-genome sequences for two novel coronaviruses from Chinese horseshoe bats are the most closely related to the severe acute respiratory syndrome coronavirus to date.

An analysis of ancient DNA from a 24,000-year-old Siberian skeleton generates a new model for the original peopling of the Western Hemisphere.

A GWAS meta-analysis identifies 11 new loci associated with onset of the neurodegenerative disease.

An academic-commercial partnership launches the largest cloud-based genomics project to date.

Researchers show that genetic enhancer elements likely contribute to face shape in mice.

Replication attempt shows that earlier claims about a genetic test for autism were overblown.

PubMed launches Commons; measuring HIV’s latent reservoir; immune-related pathway variation in genome, microbiome; rapamycin and flu vaccines; grasshopper mice resistant to pain

Researchers identify oral microbiome signatures that correlate with a person’s cultural background.

What researchers are learning as they sequence, map, and decode species’ genomes  

DNA methylation status can predict age in various human tissues, a study shows.

Nobels awarded for vesicle trafficking and computational chemistry; building 3-D microbial communities; mislabeled microbes cause retractions

Two papers on plant immunity have been retracted, and questions remain about others with similar results. 

The long-debated issue of whether mammals can use RNA interference as an antiviral defense mechanism is finally put to rest.

Genomics pioneer Craig Venter is building a new campus for his non-profit research institute right next to his alma mater in San Diego.

23andMe denies that its new patent will be used to help couples create designer babies based on personal genetic testing.

While genomic data sharing is essential for research, scientists must work to keep sensitive, potentially damaging information under wraps.

Avoiding the transmission of mitochondrial disease takes a trio, but raises a host of logistical issues.

Professor, Department of Human Genetics, University of Chicago. Age: 38

Antibiotic cycling makes a comeback in the lab; how life scientists can learn from astronauts; napping to conquer fears; deconstructing the cancer R&D crisis