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tag mass spectrometry culture immunology

Flow Cytometry for the Masses
Richard P. Grant | Dec 1, 2011 | 2 min read
Tagging antibodies with rare earth metals instead of fluorescent molecules turns a veteran technique into a high-throughput powerhouse.
One Protein to Rule Them All
Shelby Bradford, PhD | Feb 28, 2024 | 10+ min read
p53 is possibly the most important protein for maintaining cellular function. Losing it is synonymous with cancer.
Understanding Hybridoma Technology for Monoclonal Antibody Production
Understanding Hybridoma Technology for Monoclonal Antibody Production
Alpana Mohta, MD | May 9, 2023 | 5 min read
By fusing antibody-producing cells with immortal myeloma cells, researchers produce reliable supplies of highly specific antibodies.
Tumor Immunology
The Scientist Staff | Oct 29, 1995 | 3 min read
A.L. Cox, J. Skipper, Y. Chen, R.A. Henderson, T.L. Darrow, J. Shabanowitz, V.H. Engelhard, D.F. Hunt, C.L. Slingluff, "Identification of a peptide recognized by five melanoma-specific human cytotoxic T cell lines," Science, 264:716-9, 1994. (Cited in more than 60 articles through September 1995) Comments by Victor Engelhard, University of Virginia, Charlottesville The importance of this paper, according to Victor Engelhard, a professor of microbiology at the University of Virginia, is that "
Mapping Brain Proteins
Devika G. Bansal | Feb 1, 2018 | 7 min read
Researchers are using souped-up mass spectrometry to localize proteins within brain cells.
Time-Lapse Proteomics
Chandra Shekhar | Mar 1, 2007 | 4 min read
Isotope labeling and mass spectrometry unite to track proteome dynamics.
Conceptual illustration of cells releasing cytokines in various shades of blue
Spleen-to-Liver Signals Control Systemic Inflammation
Ruth Williams | Apr 29, 2021 | 3 min read
In rats, the spleen directs a cytokine surge that drives system-wide inflammation, but it is not, as once believed, the main producer of the chemical messenger.
acute myeloid leukemia aml baking soda sodium bicarbonate nabi bicarb t cell transplant stem cell infusion lactic acid cytokine ph acidosis
Baking Soda Boosts T Cells’ Ability to Fight Leukemia
Rachael Moeller Gorman | Nov 2, 2020 | 4 min read
Infusions of donor T cells to fight the cancer often fail, but sodium bicarbonate can counter lactic acid produced by leukemia cells, potentially improving remission rates in mice and humans.
lab tools cancer therapy
Contending with Resistance in Cancer Immunotherapy
Marissa Fessenden | Apr 1, 2019 | 7 min read
Researchers describe ways to study how cancer cells evade therapies that harness the immune system.
a false color transmission electron microscope image of a neuronal cell body, with lysosomes colored dark green
Scientists Uncover Major Pathway Cells Use to Mend Leaky Lysosomes
Holly Barker, PhD | Oct 6, 2022 | 3 min read
Damaged lysosomes are repaired by a lipid-based signaling pathway dubbed PITT that could be targeted to treat neurodegenerative disease, its discoverers say.

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