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image: Physical Force Upregulates Gene Expression

Physical Force Upregulates Gene Expression

By | August 24, 2016

Applying a mechanical force that pulls on a cell stretches chromatin, facilitating transcription, scientists show.

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image: Instant Messaging

Instant Messaging

By | May 1, 2016

An alternative route to sparking cell signals involves hook-ups between transmembrane and soluble ligands.

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image: Kissing Cousins

Kissing Cousins

By | May 1, 2016

Researchers discover a completely novel mechanism of cell signaling involving soluble chemokines and their transmembrane equivalents.

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image: Guts and Glory

Guts and Glory

By | April 1, 2016

An open mind and collaborative spirit have taken Hans Clevers on a journey from medicine to developmental biology, gastroenterology, cancer, and stem cells.

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image: Discoverer of G Proteins Dies

Discoverer of G Proteins Dies

By | December 29, 2015

Nobel laureate Alfred Gilman has passed away at age 74.

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image: Heady Stuff

Heady Stuff

By | November 1, 2015

New research on how fat influences brain neuronal activity

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image: A Complex Disorder

A Complex Disorder

By , and | November 1, 2015

Factors that likely contribute to obesity include disruptions to intercellular signaling, increased inflammation, and changes to the gut microbiome.  

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image: Influential Cancer Biologist Dies

Influential Cancer Biologist Dies

By | August 24, 2015

Chris Marshall, who pieced together a critical signaling pathway involved in cancer, has passed away at age 66.

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image: Control ALT, Delete Cancer

Control ALT, Delete Cancer

By , and | April 1, 2015

Treating cancer by shutting down the alternative lengthening of telomeres (ALT) pathway

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image: Short, Strong Signals

Short, Strong Signals

By | March 25, 2015

Methylation increases both the activity and instability of the signaling protein Notch.

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