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tag atp neuroscience

The Genes of Parkinsonā€™s Disease
Bobby Thomas and M. Flint Beal | Feb 1, 2011 | 10 min read
The minority of Parkinson’s cases now known to have genetic origins are shedding light on the cellular mechanisms of all the rest, bringing researchers closer to a cause—and perhaps a cure.
Guiding light
Amber Dance | Dec 1, 2009 | 7 min read
ul li { font-family:"Trebuchet MS",arial,helvetica; font-size:10.5pt; line-height:14pt; } By Amber Dance Guiding light How to manipulate cellular events with the right light sensing molecule and a flash of light. Using light-producing molecules to observe cellular events is standard fare in many a lab, but it’s only recently that scientists have begun to harness the power of light to manipulate biological systems experimen
The Movement of Goods Around the Cell
Patricia Bassereau and Bruno Goud | Apr 1, 2011 | 10+ min read
A biologist and a physicist collaborate on a decade-long exploration of the physical parameters of membrane traffic in eukaryotic cells.
The Movement of Goods Around the Cell
Patricia Bassereau and Bruno Goud | Apr 1, 2011 | 9 min read
By Patricia Bassereau and Bruno Goud The Movement of Goods Around the Cell A biologist and a physicist collaborate on a decade-long exploration of the physical parameters of membrane traffic in eukaryotic cells. 3-D reconstruction of confocal images showing membrane tubes pulled from a giant unilamellar vesicle by kinesin motors along microtubules. The tube diameter is about 100 nm and the vesicle diameter about 15 μm.Courtesy of Cécile Leduc In proka
Assays by the Score
Deborah Fitzgerald | May 27, 2001 | 9 min read
Click to view the PDF file: Bead-based Fluorescent Multiplex Protein Analysis Systems Courtesy of LINCO ResearchLabMAP-based systems use internally dyed fluorescent microspheres to analyze as many as 100 different analytes concurrently. Today's competitive, high-paced research environment has stimulated the development of a host of approaches for rapid, cost-efficient analyses of large numbers of samples. In keeping with this trend, methods for simultaneously analyzing multiple species in a g
Death Watch II: Caspases and Apoptosis
Jorge Cortese | Jun 24, 2001 | 10 min read
Caspase Related Reagents Courtesy of Bingren Hu, Queen's Medical Center, Hawaii. Provided by Cell Signaling TechnologyConfocal micrograph of double immunostaining for cleaved caspase-3 (green) and propidium iodide (red) in newborn rat brain tissue. This section shows control and transient cerebral ischemia. Editor's Note: This is the second article in our two-part series on cell death. The first part: J. Cortese, "Death watch I: Cytotoxicity detection," The Scientist, 15[5]:26, March 5, 2001.
Ten Technologies in Five Years
Sam Jaffe(sjaffe@the-scientist.com) | Dec 5, 2004 | 8 min read
When scientists make long-term research plans, they must try to anticipate how emerging technologies will influence their work in the coming years.
Cell-Signaling A Cascade of Kinases, Phosphatases, and Cytokines
Deborah Noble | Jul 4, 1999 | 8 min read
Date: July 5, 1999Table of Cell Signaling Tools At today's research pace, new signaling mechanisms within and between cells are emerging not one by one but in a chain reaction. Each new discovery has strong implications for previously established models, sometimes overturning several assumptions at once. With such a large number of interacting systems--from cell adhesion to differentiation and apoptosis--and receptor pathways, keeping up with the wealth of cell-signaling research tools can be l

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