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Combined transcription and genome data from multiple tissues in hundreds of human donors reveal links between genotype and gene expression across the body.

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image: Live Cell Extractions

Live Cell Extractions

By | October 1, 2017

Nanostraws that collect specimens from cells without killing them allow for repeated sampling.

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image: Sex Reversal Mystery Explained?

Sex Reversal Mystery Explained?

By | June 15, 2017

A proposed mechanism for how bearded dragons with male chromosomes hatch as females at high temperatures

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Adding RNA sequencing analysis to genomic sequencing helps scientists uncover mutations likely responsible for genetic disorders they might otherwise miss.

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image: Massively Parallel Perturbations

Massively Parallel Perturbations

By | March 1, 2017

Scientists combine CRISPR gene editing with single-cell sequencing for genotype-phenotype screens.

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image: Infographic: Single-Cell CRISPR Screens

Infographic: Single-Cell CRISPR Screens

By | March 1, 2017

See how two new methods track responses to unique genetic manipulations in numerous individual cells in parallel.

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Researchers solve the mystery of 15-year-old mutant ferns with disrupted sex determination.

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image: Noncoding RNAs Not So Noncoding

Noncoding RNAs Not So Noncoding

By | June 1, 2016

Bits of the transcriptome once believed to function as RNA molecules are in fact translated into small proteins.

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image: Aneuploid Responses

Aneuploid Responses

By | May 1, 2016

A recent exchange of papers is divided over the evidence for compensatory gene expression among wild strains of aneuploid yeast.

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image: Scaling to Singles

Scaling to Singles

By | May 1, 2016

Tips for tracing transcription in individual cells

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